Results 51 to 60 of about 9,755,981 (243)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

DETERMINANTS OF THE GENESIS OF HISTORICAL EDUCATION AND SCIENCE IN THE FRAMEWORK OF THE SIBERIAN SCIENTIFIC-EDUCATIONAL COMPLEX: SYNTHESIS OF METHODOLOGICAL APPROACHES

open access: yesВестник Кемеровского государственного университета, 2017
The article is devoted to analysis of the experience of methodological synthesis, carried out during the reconstruction of the historical evolution of science and higher historical education in Siberia. In relation to the object of study three approaches
Dmitry V. Khaminov
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Marginalisation et dépendance aérienne de l’Afrique sub-saharienne

open access: yesBelgeo, 2007
The place of sub-Saharan Africa in the world air system and the question of domestic flights in Africa are addressed in this paper, which analyzes the problems raised by air operation on that continent and fuels the discussion on regulation ...
Frédéric Dobruszkes   +1 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

EFFECT OF POSITIONAL DENSITY ON DC CONDUCTIVITY OF BAMBOO

open access: yesBioResources, 2010
In the present communication, the effect of positional density on the DC electrical conductivity of bamboo fibres was studied. A comparative study was made between the DC conductivity behavior of bamboo fibres taken from upper and lower portions of ...
Navin Chand   +3 more
doaj  

Centre, Periphery and Back

open access: yesHistorein
This special issue consists of a collection of six articles by Greek historians of the periphery of Europe that look at the perplexities and challenges of European historiography of the centre. Their analysis aims to interpret pivotal moments that have shaped recent historiographies in tackling the advance of global history, and the successful or ...
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Centre and Periphery in Romance Literatures [PDF]

open access: yes, 2021
Le colloque a rassemblé les spécialistes de la problématique concenant la relation entre le centre et les périphéries dans les littératures romanes.Na konferenci se sešli odborníci na problematiku vztahu centra a periferie v románsk& literaturách.The
Kyloušek Petr
core  

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