Results 121 to 130 of about 4,506,201 (347)
Harmonized multi‐metric and multi‐centric assessment of EEG source space connectivity for dementia characterization [PDF]
Pavel Prado +11 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Grandeurs et déclin du centre d’interprétation
Les centres d’interprétation semblent avoir la cote ces jours-ci. Bien avant que des centres d’interprétation, comme celui qui aurait pu pérenniser la bataille du Long-Sault, permettent de rappeler aux sens ce qu’il n’était plus possible de voir, l ...
Luc Noppen, Lucie K. Morisset
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
The Impact of Foundation Medicine Testing on Cancer Patients: A Single Academic Centre Experience [PDF]
Dalia Karol +5 more
openalex +1 more source

