Results 121 to 130 of about 4,708,577 (333)
Élaboration d'indicateurs de qualité de soins dans un centre hospitalier psychiatrique
I. Gory +2 more
openalex +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Non-muscle myosin II takes centre stage in cell adhesion and migration
M. Vicente-Manzanares +3 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Livsvärldar och globalisering i Lukas Moodyssons "Mammut"
In 2009, Lukas Moodysson’s motion picture Mammoth had its opening. The movie is set in three different locations – New York, Thailand, and the Philippines – and follows several characters and their individual life stories. In Swedish and Anglo-Saxon news
Magnus Rodell
doaj
Grandeurs et déclin du centre d’interprétation
Les centres d’interprétation semblent avoir la cote ces jours-ci. Bien avant que des centres d’interprétation, comme celui qui aurait pu pérenniser la bataille du Long-Sault, permettent de rappeler aux sens ce qu’il n’était plus possible de voir, l ...
Luc Noppen, Lucie K. Morisset
doaj

