Results 131 to 140 of about 12,577,314 (296)

Centre for Effective Services: strategy 2012 – 2014 and beyond [PDF]

open access: yes, 2012
The Centre for Effective Services (CES) was established in 2008 in the Republic of Ireland, and in 2010 in Northern Ireland. The overall remit of the centre was to provide technical and organisational ‘expertise’ to promote and support the application of
Centre for Effective Services
core  

Humanistyka: pracownia, centrum czy laboratorium?

open access: yesTeksty Drugie, 2017
The fact that laboratories are becoming increasingly popular in the humanities forces us to think about the field’s structural transformation – its sources, meaning and consequences.
Urszula Pawlicka
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Asia Centre labellisé Think Tank & Transparent 2016

open access: yes, 2017
Asia Centre a reçu le label Think Tank & Transparent 2016, attribué par l’Observatoire Européen des Think-tanks. Cette distinction, basée sur l’évaluation du fonctionnement de la structure (gouvernance, transparence, production et communication) souligne
Asia Centre
core  

Crop Protection Centre

open access: yes, 2014
In 1990 the Wageningen Centre for Crop Protection was established by the Wageningen Agricultural University (WAU) and the Research Institute for Plant Protection (IPO). The Centre was created as a response to the increasing number of activities..
Technical Centre for Agricultural and Rural Cooperation
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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