Results 131 to 140 of about 8,524,884 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
In 1990 the Wageningen Centre for Crop Protection was established by the Wageningen Agricultural University (WAU) and the Research Institute for Plant Protection (IPO). The Centre was created as a response to the increasing number of activities..
Technical Centre for Agricultural and Rural Cooperation
core
Digital Curation Centre – Phase Two
An overview of the Digital Curation Centre since its establishment in 2004, including accomplishments of Phase One, aims and objectives of Phase Two, and how DCC relates to JISC ...
Hockx-Yu, Helen, Helen Hockx-Yu
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The El Nino-induced abnormal weather tends to be increasing in its frequency of occurrence, magnitude, duration and irregularity in recent years. Accordingly, it is urgent for rainfed upland agriculture, where most CGPRT crops are grown, to establish ...
CGPRT Centre, UN.ESCAP, Irawan, Bambang
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Livsvärldar och globalisering i Lukas Moodyssons "Mammut"
In 2009, Lukas Moodysson’s motion picture Mammoth had its opening. The movie is set in three different locations – New York, Thailand, and the Philippines – and follows several characters and their individual life stories. In Swedish and Anglo-Saxon news
Magnus Rodell
doaj

