Results 131 to 140 of about 8,524,884 (312)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Crop Protection Centre

open access: yes, 2014
In 1990 the Wageningen Centre for Crop Protection was established by the Wageningen Agricultural University (WAU) and the Research Institute for Plant Protection (IPO). The Centre was created as a response to the increasing number of activities..
Technical Centre for Agricultural and Rural Cooperation
core  

Digital Curation Centre – Phase Two

open access: yes, 2007
An overview of the Digital Curation Centre since its establishment in 2004, including accomplishments of Phase One, aims and objectives of Phase Two, and how DCC relates to JISC ...
Hockx-Yu, Helen, Helen Hockx-Yu
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Stabilization of upland agriculture under El Nino induced climatic risk : impact assessment and mitigation measures in Indonesia

open access: yes, 2002
The El Nino-induced abnormal weather tends to be increasing in its frequency of occurrence, magnitude, duration and irregularity in recent years. Accordingly, it is urgent for rainfed upland agriculture, where most CGPRT crops are grown, to establish ...
CGPRT Centre, UN.ESCAP, Irawan, Bambang
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Livsvärldar och globalisering i Lukas Moodyssons "Mammut"

open access: yesTidsskrift for Kulturforskning
In 2009, Lukas Moodysson’s motion picture Mammoth had its opening. The movie is set in three different locations – New York, Thailand, and the Philippines – and follows several characters and their individual life stories. In Swedish and Anglo-Saxon news
Magnus Rodell
doaj  

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