Results 51 to 60 of about 50,603 (296)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Flow–thermal analysis of ventilation and cooling capacity of centrifugal fans with splitter blades in high-voltage asynchronous motors [PDF]

International Journal of Fluid Engineering
High-voltage asynchronous motors (HVAMs) face the problem of excessive internal temperatures during operation, which not only compromises operational safety, but may also shorten their service life.
Houbin Song, Xiaolong Huang, Hongbo Qiu, Wei Han, Yukun Zhang, Shuai Wang, Wenqi Xie   +6 more
doaj   +1 more source

The influence of bearings disalignment on rotor deflection [PDF]

, 2014
В работе проведено теоретическое исследование влияния величины несоосного расположения подшипниковых опор ротора центробежного шахтного вентилятора главного проветривания (ВЦД-4,7) на значение статического и динамического прогиба вала ротора.Conducted ...
Marenko, Vladislav, Plahotnik, Valentina, Vanga, Gennady, Ванжа, Геннадий Куприянович, Ванжа, Геннадій Купріянович, Марьенко, Владислав Николаевич, Мар’єнко, Владислав Миколайович, Плахотник, Валентина Васильевна, Плахотнік, Валентина Василівна   +8 more
core  

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Failure Maps for Rectangular 17-4PH Stainless Steel Sandwiched Foam Panels [PDF]

, 2007
A new and innovative concept is proposed for designing lightweight fan blades for aircraft engines using commercially available 17-4PH precipitation hardened stainless steel.
Ghosn, L. J., Raj, S. V.
core   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Deformable bearing seat [PDF]

, 1977
A deformable bearing seat is described for seating a bearing assembly in a housing. The seat includes a seating surface in the housing having a first predetermined spheroidal contour when the housing is in an undeformed mode.
Moreman, O. S., III
core   +1 more source

Noise generation in FC centrifugal fans [PDF]

The Journal of the Acoustical Society of America, 1978
Sources of broadband noise in FC (forward curved blades) centrifugal fans were studied experimentally using a 0.28-m-diameter fan. Strong tangential and axial gradients of mean velocity and static pressure were found in the housing. Very large variations in velocity and velocity fluctuations occurred across the blade passages, from the suction surface ...
W. B. Swim, D. Raj
openaire   +1 more source

Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

Advanced Science, EarlyView.
This study examined the translation activity across ten stages of maize anther development, integrating transcriptome and small‐peptide data. It linked mutations in translated 3' ORFs to anther sterility, exemplified by Zm00001eb417050_3' ORF (known as APV1). In addition, the data indicated that maize anthers could assimilate CO2 through the stomata in
Chunyu Wang, Yuechao Wu, Shunxi Wang, Han Liu, Siqi Jiang, Yingjia Han, Liuji Wu, Tao Zhang, Mei Zhang   +8 more
wiley   +1 more source

Simulation of Entropy Generation under Stall Conditions in a Centrifugal Fan

Entropy, 2014
Rotating stalls are generally the first instability met in turbomachinery, before surges. This 3D phenomenon is characterized by one or more stalled flow cells which rotate at a fraction of the impeller speed. The goal of the present work is to shed some
Lei Zhang, Jinhua Lang, Kuan Jiang, Songling Wang   +3 more
doaj   +1 more source