Results 41 to 50 of about 3,262 (203)

Extensive Phytochemical Assessment of Hook (Orchidaceae)

Natural Product Communications, 2022
Dendrobium fimbriatum Hook is an important medicinal and ornamental orchid that may lead to important drugs and cosmetics. In this study, 2 analytical strategies were combined to describe the detailed composition of a hydroethanolic extract of the whole ...
Quentin Favre-Godal, Jane Hubert, Alexis Kotland, Delphine Garnier, Camille Beaugendre, Lorène Gourguillon, Aurelie Urbain, Sonia Lordel-Madeleine, Patrick Choisy   +8 more
doaj   +1 more source

Countercurrent chromatography in analytical chemistry (IUPAC technical report)

, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Sutherland, IA, Ian A. Sutherland, Tatyana Maryutina, Maryutina, T, Spivakov, B, Boris Spivakov, Shpigun, O, Berthod, A, Alain Berthod, Oleg Shpigun   +9 more
core   +1 more source

Structural Elucidation of Novel Saponins in the Sea Cucumber Holothuria lessoni

Marine Drugs, 2014
Sea cucumbers are prolific producers of a wide range of bioactive compounds. This study aimed to purify and characterize one class of compound, the saponins, from the viscera of the Australian sea cucumber Holothuria lessoni.
Yadollah Bahrami, Wei Zhang, Tim Chataway, Chris Franco   +3 more
doaj   +1 more source

Centrifugal partition chromatography in a biorefinery context: Optimisation and scale-up of monosaccharide fractionation from hydrolysed sugar beet pulp [PDF]

, 2017
The isolation of component sugars from biomass represents an important step in the bioprocessing of sustainable feedstocks such as sugar beet pulp.
Hewitson, Peter, Lye, Gary J., Alba Díaz-Rodríguez, Douillet, N, David J. Leak, Hamley-Bennett, Charlotte, Diaz-Rodriguez, A, Ignatova, S, Douillet, Nathalie, Leak, DJ, Gary J. Lye, Lye, GJ, Charlotte Hamley-Bennett, Hamley-Bennett, C, Leak, David J., Cardenas-Fernandez, M, Adams, JP, Joseph P. Adams, Svetlana Ignatova, Adams, Joseph P., Peter Hewitson, Cárdenas-Fernández, Max, David P. Ward, Max Cárdenas-Fernández, Hewitson, P, Ward, David P., Ward, DP, Nathalie Douillet, Ignatova, Svetlana, Díaz-Rodríguez, Alba   +29 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Isolation of N-Ethyl-2-pyrrolidinone-Substituted Flavanols from White Tea Using Centrifugal Countercurrent Chromatography Off-Line ESI-MS Profiling and Semi-Preparative Liquid Chromatography

Molecules, 2021
N-Ethyl-2-pyrrolidinone-substituted flavanols (EPSF) are marker compounds for long-term stored white teas. However, due to their low contents and diasteromeric configuration, EPSF compounds are challenging to isolate.
Weidong Dai, Maria Ramos-Jerz, Dongchao Xie, Jiakun Peng, Peter Winterhalter, Gerold Jerz, Zhi Lin   +6 more
doaj   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Purification of green fluorescent protein using fast centrifugal partition chromatography

, 2021
The green fluorescent protein (GFP) is a biomolecule used in many biological applications such as biomarkers and biosensors, which require high purity levels.
Coutinho, João A. P., Santos, João H.P.M., Santos-Ebinuma, Valéria C., Freire, Mara G., Pereira, Jorge F.B. [UNESP], Martins, Margarida, Santos-Ebinuma, Valéria C. [UNESP], Santos, Nathalia V. [UNESP], Ventura, Sónia P.M., Soares, Bruna P., Santos, Nathalia V., Pereira, Jorge F. B., Ventura, Sónia P. M., Santos, João H. P. M., Coutinho, João A.P., Almeida, Mafalda R.   +15 more
core   +1 more source