Extraction of cocoa proanthocyanidins and their fractionation by sequential centrifugal partition chromatography and gel permeation chromatography [PDF]
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)Cocoa beans contain secondary metabolites ranging from simple alkaloids to complex polyphenols with most of them believed to possess significant health benefits.
A Marston +25 more
core +1 more source
Lipid-free Antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties [PDF]
Background: The hydatid disease parasite Echinococcus granulosus has a restricted lipid metabolism, and needs to harvest essential lipids from the host.
Córsico, Betina +5 more
core +5 more sources
Clarification of the Saponin Composition of Tubers
Six known saponins, glycosides of hederagenin and oleanolic acid, have been isolated from the tubers of Ranunculus ficaria L. (Ranunculaceae). Their separation included the use of centrifugal partition chromatography (CPC).
Andrew Marston +5 more
doaj +1 more source
Extensive Phytochemical Assessment of Hook (Orchidaceae)
Dendrobium fimbriatum Hook is an important medicinal and ornamental orchid that may lead to important drugs and cosmetics. In this study, 2 analytical strategies were combined to describe the detailed composition of a hydroethanolic extract of the whole ...
Quentin Favre-Godal +8 more
doaj +1 more source
High resolution spectroscopy of methyltrioxorhenium: towards the observation of parity violation in chiral molecules [PDF]
Originating from the weak interaction, parity violation in chiral molecules has been considered as a possible origin of the biohomochirality. It was predicted in 1974 but has never been observed so far.
Alexander Shelkovnikov +70 more
core +3 more sources
Diffusion of solvent from a cast cellulose acetate solution during the formation of skinned membranes [PDF]
The transport of solvent out of a cast cellulose acetate (CA) solution into the coagulation bath during membrane formation is treated as a diffusion process.
Altena, F.W. +4 more
core +3 more sources
Structural Elucidation of Novel Saponins in the Sea Cucumber Holothuria lessoni
Sea cucumbers are prolific producers of a wide range of bioactive compounds. This study aimed to purify and characterize one class of compound, the saponins, from the viscera of the Australian sea cucumber Holothuria lessoni.
Yadollah Bahrami +3 more
doaj +1 more source
Transport and binding of tumor necrosis factor-α in articular cartilage depend on its quaternary structure [PDF]
The effect of tumor necrosis factor-α (TNFα) on cartilage matrix degradation is mediated by its transport and binding within the extracellular matrix (ECM) of the tissue, which mediates availability to cell receptors.
Aderka +41 more
core +1 more source
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

