Results 151 to 160 of about 1,302,968 (344)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Bacterial Removal Separation with a Reduced Throughput Adapted for Artisan Cheese Dairies—Effect on Clostridial Spore Counts and Milk Quality

Dairy
Late blowing is a prevalent and costly cheese defect caused by clostridia. In organic cheese production, the use of additives that inhibit the growth of clostridia is prohibited.
Nicole Wente, Christian Zscherpe, Stefanie Leimbach, Paula Mallast, Anne Tellen, Yanchao Zhang, Saskia Schwermann, Volker Krömker   +7 more
doaj   +1 more source

The impact of the centrifuge characteristics and centrifugation protocols on the cells, growth factors, and fibrin architecture of a leukocyte- and platelet-rich fibrin (L-PRF) clot and membrane

Platelets, 2018
D. D. Dohan Ehrenfest, N. Pinto, Andrea Pereda, P. Jiménez, M. Del Corso, Byung-Soo Kang, M. Nally, N. Lanata, Hom-lay Wang, M. Quirynen   +9 more
semanticscholar   +1 more source

Centrifugation-induced fibrous orientation in fish-sourced collagen matrices

, 2017
An aligned fibrous collagen matrix is fabricated at the macroscale by centrifugation.
Yan Zhao, Lang He, Cristiano L. P. Oliveira, Chengzhi Xu, Yang Sun, Benmei Wei, Juntao Zhang, Haibo Wang   +7 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Recovery of poly-3-hydroxybutyrate from recombinant Escherichia coli by homogenization and centrifugation

, 1997
Poly-3-hydroxybutyrate from recombinant E. coli was recovered using homogenization and continuous centrifugation with a purity of 94%. Final protein and DNA concentrations were 1.0% w/w and 1.9% w/w, respectively, when a hypochlorite treatment was ...
Thomas, CJ, Middelberg, APJ, Ling, Y., Williams, D., Middelberg, A., Ling, Y, Williams, DRG, Thomas, C.   +7 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Hematocrit Centrifuge [PDF]

Science, 1975
openaire   +2 more sources

Use of Centrifugation Technique to Purify Water from Bacteria

, 2012
Use of Centrifugation technique to Purify Water from ...
Mustafa, Zeinab
core