Results 161 to 170 of about 1,676,115 (338)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Rapid isolation and purification of mitochondria for transplantation using tissue dissociation and differential filtration [PDF]

open access: yes, 2016
Researchers have identified several methods for treating acute myocardial infarction (AMI) patients affected by ischemia and reperfusion injury. Some of these therapies include thrombolysis, balloon angioplasty, and coronary arterial bypass graft (CAGB).
Preble, Janine Marie
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Determination of residue content of seawater-based on-line mixing polymer fracturing fluid by vacuum filtration method

open access: yesGongye shui chuli
In response to the inability of centrifugation to accurately detect the residue content of seawater-based on-line mixing polymer fracturing fluid, a vacuum filtration method was proposed.
JUAN Peng, LIANG Yuan, DU Ying
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Study of physiological tolerance to centrifugation Final report [PDF]

open access: yes
Physiological effects and acceleration tolerances after weightlessness based on space environment simulation with human centrifuges and bed ...
Benedict, J. V.   +3 more
core   +1 more source

Proses Penghasilan Bromelin daripada Batang Nenas [PDF]

open access: yes, 1990
A proteolytic enzyme called bromelin can be produced from pineapple stem by precipitating it from pineapple stem juice and separating the precipitate from the juice. Acetone is used as the precipitant.
Krishna Rao, D. S   +2 more
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Chromatin Structure in the Cellular Slime Mold Dictyostelium discoideum [PDF]

open access: yes, 1978
The structure of Dictyostelium discoideum chromatin has been studied by the following techniques: electron microscopy, staphylococcal nuclease digestion, acrylamide gel electrophoresis, sucrose gradient centrifugation, and melting.
Bakke, Antony C.   +2 more
core  

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