Results 71 to 80 of about 1,582,967 (422)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Vertical Structure of the Transition Zone from Infalling Rotating Envelope to Disk in the Class 0 Protostar, IRAS04368+2557 [PDF]

open access: yesMNRAS 467 (2017) L76-L80, 2017
We have resolved for the first time the radial and vertical structure of the almost edge-on envelope/disk system of the low-mass Class 0 protostar L1527. For that, we have used ALMA observations with a spatial resolution of 0.25$^{\prime\prime}$$\times$0.13$^{\prime\prime}$ and 0.37$^{\prime\prime}$$\times$0.23$^{\prime\prime}$ at 0.8 mm and 1.2 mm ...
arxiv   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

The Centrifugal Emulsor [PDF]

open access: yesScientific American, 1892
n ...
openaire   +2 more sources

Centrifugal Etching

open access: yesJournal of The Electrochemical Society, 2003
A cell consisting of a rotatable double-walled cylinder is described for the study of etching under conditions of enhanced gravity. Rotation rates of 6000 revolutions per minute giving g values of up to 600 were possible with the set-up. The cell was tested by etching masked patterns in a copper plate with an aqueous FeCl3 solution.
Tijburg, L.B.M   +3 more
openaire   +5 more sources

Separation of gas mixtures by centrifugation [PDF]

open access: yes, 1972
Magnetohydrodynamic (MHD) centrifuge utilizing electric currents and magnetic fields produces a magnetic force which develops supersonic rotational velocities in gas mixtures.
Love, W. L., Park, C.
core   +1 more source

Puromycin Sensitivity of Ribosomal Label after Incorporation of 14C-Labelled Amino Acids into Isolated Mitochondria from Neurospora crassa [PDF]

open access: yes, 1969
Radioactive amino acids were incorporated into isolated mitochondria from Neurospora crassa. Then the mitochondrial ribosomes were isolated and submitted to density gradient centrifugation. A preferential labelling of polysomes was observed.
Dingman C. W.   +8 more
core   +2 more sources

On-Chip Generation of Vortical Flows for Microfluidic Centrifugation.

open access: yesSmall, 2019
Microcentrifugation constitutes an important part of the microfluidic toolkit in a similar way that centrifugation is crucial to many macroscopic procedures, given that micromixing, sample preconcentration, particle separation, component fractionation ...
H. Ahmed   +4 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Separation of brewer pellets in a vibratory-centrifugal centrifuge [PDF]

open access: yesBIO Web of Conferences, 2020
The article reflects the process of dehydration of brewer pellets, as one of the ways to solve the problem of their utilization in order to obtain a highly concentrated feed for farm animals, which is an urgent task. The purpose of the study is to substantiate the interrelation between the technological and physical properties of the brewer pellets ...
Marat Akhmetvaliyev   +5 more
openaire   +2 more sources

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