Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Space Station Centrifuge: A Requirement for Life Science Research [PDF]
A centrifuge with the largest diameter that can be accommodated on Space Station Freedom is required to conduct life science research in the microgravity environment of space.
Fuller, Charles A. +3 more
core +1 more source
The real time mass evaluation system as a tool for detection of undeclared cascade operation at GCEPs [PDF]
, 2008 Given the flexibility of current cascade designs a real time mass monitoring system is preferred for safeguarding Gas Centrifuge Enrichment Plants.
Delbeke, J.F.A. +4 more
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Stallion Sperm Viability, as Measured by the Nucleocounter SP-100, Is Affected by Extender and Enhanced by Single Layer Centrifugation [PDF]
, 2009 Jane M. Morrell +6 more
openalex +1 more source
A comparative study of land-based and sea-based site responses based on centrifuge model testing [PDF]
, 2022 Juan Liu +4 more
openalex +1 more source
Continuous Centrifuge Decelerator for Polar Molecules
, 2013 Producing large samples of slow molecules from thermal-velocity ensembles is a formidable challenge. Here we employ a centrifugal force to produce a continuous molecular beam with a high flux at near-zero velocities.
Bayerl, J. +6 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Design and Economic Analysis of Solid Control System for Coiled Tubing Drilling
Shiyou jixieTo solve the problems of high energy consumption， large floor area and insufficient environmental protection performance of traditional coiled tubing drilling （CTD） solid control system， a two-stage optimized solid control system scheme based on high ...
Yang Lin +4 more
doaj
Description of a double centrifugation tube method for concentrating canine platelets [PDF]
, 2013 Anna Perazzi +7 more
openalex +1 more source