Results 171 to 180 of about 603,245 (381)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Design of a piezoelectric shaker for centrifuge testing [PDF]
The design of a prototype piezoelectric shaker and its development to date is described. Although certain design problems remain to be solved, the piezoelectric system shows promise for adaptation to a larger payload system, such as the proposed ...
Canclini, J. G., Henderson, J. M.
core +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Voice integrated systems [PDF]
The program at Naval Air Development Center was initiated to determine the desirability of interactive voice systems for use in airborne weapon systems crew stations.
Curran, P. Mike
core +1 more source
The isolation of histamine from the white cell layer of centrifuged rabbit blood
Charles F. Code, H. R. Ing
openalex +2 more sources
AN IMPROVED METHOD FOR THE ISOLATION OF RAT LIVER NUCLEI BY DENSITY CENTRIFUGATION [PDF]
D. Michael Gill
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Notizen: Density Gradient Centrifugation of Reovirus Prototypes 1, 2 and 3 [PDF]
Magdy Fouad, Reto Engler
openalex +1 more source