Results 91 to 100 of about 1,590,241 (290)

Ground collapse: effect of building position on tunnelling-induced soil movements

open access: yesGeohazard Mechanics
The mechanisms of tunnelling-induced ground movements are important for risk assessments of tunnelling beneath masonry buildings with shallow foundations, including ground collapse disasters.
Chuanjin Tang, Alec M. Marshall
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Centrifuge modelling of jacket foundation subjected to cyclic lateral loading in soft clay

open access: yesYantu gongcheng xuebao, 2018
The centrifugal model tests are carried out on a jacket foundation subjected to cyclic lateral loading in saturated soft clay to investigate the force and deformation characteristics of the jacket foundation under cyclic lateral loading from wind and ...
ZHU Shu , CHEN Ren-peng
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Static and dynamic rocking stiffness of shallow footings on sand: centrifuge modelling

open access: yes, 2018
Small-strain foundation response has mostly been studied analytically, with limited experimental verification against 1g physical model tests. This paper revisits the problem of small-strain foundation response, conducting a series of centrifuge model ...
Jan Laue   +9 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Submarine landslide flows simulation through centrifuge modelling [PDF]

open access: yes, 2012
Landslides occur both onshore and offshore. However, little attention has been given to offshore landslides (submarine landslides). Submarine landslides have significant impacts and consequences on offshore and coastal facilities.

core   +2 more sources

Centrifuge modelling of dry granular run-out processes under deflective Coriolis condition

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Coriolis effects, encompassing the dilative, compressive, and deflective manifestations, constitute pivotal considerations in the centrifugal modelling of high-speed granular run-out processes.
Bei Zhang, Yandong Bi, Yu Huang
doaj   +1 more source

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