Results 101 to 110 of about 48,590 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Overview geotechnical model tests on dike safety at Deltares [PDF]

, 2012
Three on-going dike safety studies (on: macro stability, piping and flow slides) in the Netherlands make use of geotechnical physical models. A short outline of these projects is presented; the physical models chosen are described and discussed.
Bezuijen, Adam, Van Beek, Vera, Van Den Ham, GA, Zwanenburg, C   +3 more
core   +1 more source

Multistep introduction of bacteria to natural substrates at different initial inoculation doses [PDF]

, 2009
The population dynamics of the saprotrophic Pseudomonas fluorescens 32 gfp bacteria and two conventionally pathogenic enterobacteria (Escherichia coli 0157:H7 and Salmonella enterica var.
Bruggen, A.H.C., van, Kunenkova, N.N., Kupriyanov, A.A., Semenov, A.M.   +3 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Centrifuge modelling of screw piles for offshore wind energy foundations [PDF]

, 2018
Screw piles (helical piles) can provide a viable, cost-effective and low-noise installation alternative to increasing the size of existing foundation solutions (e.g.
Al-Baghdadi, T., Augarde, C.E., Ball, J., Blake, A., Brennan, A., Brown, M.J., Coombs, W.M., Davidson, C., Divall, Sam, Goodey, Richard, Knappett, J., McNamara, Andrew, Panchal, Jignasha, Richards, D., Stallebrass, Sarah, Taylor, Neil, Wang, L.   +16 more
core   +19 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Application of simple cascade GPC with robust behaviour to a sugar refinery [PDF]

, 1999
This paper presents the application of a Generalized Pre dictive Controller (GPC) to sludge density control in a sugar factory. The loop is controlled by a cascade strategy where both the master and the slave controllers are predic tive ones.
Bordons Alba, Carlos, Camacho, Eduardo F.   +1 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Centrifuge modelling of dry granular run-out processes under deflective Coriolis condition

Journal of Rock Mechanics and Geotechnical Engineering
Coriolis effects, encompassing the dilative, compressive, and deflective manifestations, constitute pivotal considerations in the centrifugal modelling of high-speed granular run-out processes.
Bei Zhang, Yandong Bi, Yu Huang
doaj   +1 more source

Математическое моделирование процесса разделения суспензии на фильтре с самоочищающимся фильтрующим элементом [PDF]

, 2016
Математична модель може бути застосована при розрахунку параметрів процесу фільтрування суспензії на фільтрі із самоочисним фільтрувальним елементом.Отримана математична модель ґрунтується на моделі процесу фільтрування із закупорюванням кожної пори ...
Кравець, Олег Ігорович, Шинкарик, Марія Миколаївна   +1 more
core