Gene expression profiling of Burkholderia cenocepacia at the time of cepacia syndrome: loss of motility as a marker of poor prognosis? [PDF]
ABSTRACT Cepacia syndrome (CS) is a fatal septic condition that develops in approximately 20% of cystic fibrosis (CF) patients chronically infected with the Burkholderia cepacia complex (Bcc). The most common causative agent is Burkholderia cenocepacia , a clinically dominant Bcc ...
Kalferstova L +4 more
europepmc +5 more sources
Cepacia syndrome in a cystic fibrosis patient colonised with Burkholderia multivorans. [PDF]
The authors present the case of an 18-year-old girl with cystic fibrosis. Her genotype was F508/N1303K. She had sputum colonisation by Pseudomonas aeruginosa and Staphylococcus aureus and since 2006, she also had Burkholderia cepacia in sputum, which was typed as genomovar II ( Burkholderia multivorans ).
Shafiq I +3 more
europepmc +5 more sources
Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing [PDF]
IntroductionThe Burkholderia cepacia complex encompasses a group of gram-negative opportunistic pathogens that cause chronic lung infections in people with cystic fibrosis.
Amy Pham +15 more
doaj +3 more sources
A 26‐year‐old female was referred to us with left eye microbial keratitis following laser in‐situ keratomileusis (LASIK) done a month ago. The vision was 20/1200. The left eye had a central infiltrate involving the flap and beyond [Fig. 1].
Vaibhav Kanduri +3 more
doaj +4 more sources
Successful treatment of cepacia syndrome [PDF]
a Departments of Paediatrics and Child Health, University of Otago, Wellington, Wellington Hospital, Capital and Coast Health, PO Box 7343, Wellington 6015, New Zealand b Queensland Paediatric Infectious Diseases Laboratory, Queensland Children's Medical Research Institute, Royal Children's Hospital, School of Medicine, University of Queensland ...
Grimwood, K, Kidd, T J, Tweed, M
openaire +3 more sources
AbstractBackgroundCepacia syndrome (CS) is an acute, necrotizing pneumonia with a high mortality rate, occurring in patients with cystic fibrosis (CF) infected with Burkholderia cepacia complex (BCC). Due to its low incidence, data on this condition are limited.MethodsWe conducted a systematic review of the reported cases of CS by searching MEDLINE ...
Dacco V. +6 more
openaire +3 more sources
Successful Lung Re-transplant in a Patient with Cepacia Syndrome due to Burkholderia ambifaria [PDF]
Chronic airway inflammation and infection drive morbidity and mortality among patients with cystic fibrosis (CF). While Haemophilus influenzae and Staphylococcus aureus predominate in children, the prevalence of Pseudomonas aeruginosa increases as patients age.
Kellie J, Goodlet +6 more
openaire +3 more sources
‘Cepacia syndrome’ with Burkholderia multivorans, 9 years after initial colonization [PDF]
A 16-year-old boy with cystic fibrosis developed 'cepacia syndrome' 9 years after the first isolation of Burkholderia multivorans. It is important to recognise that 'cepacia syndrome' is not restricted to those infected with genomovar type III strains and that rapid, irreversible clinical decline can occur many years after the 1st isolation of ...
Blackburn, L +3 more
openaire +3 more sources
Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy [PDF]
We report the case of successful treatment of a 31-year-old lady with cystic fibrosis and an en-bloc liver-pancreas transplant, who developed cepacia syndrome on a background of chronic infection with the ET12 epidemic strain of Burkholderia cenocepacia.
Weidmann, A. +3 more
openaire +3 more sources
Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids [PDF]
Burkholderia cepacia complex (BCC) is a group of 17 closely related bacterial species that can cause pulmonary infection in patients with cystic fibrosis (CF). The clinical manifestations of BCC infection are varied but can include cepacia syndrome, which is a rapidly progressing necrotising pneumonia with an almost universally fatal outcome. We report
Gilchrist, Francis J. +3 more
openaire +3 more sources

