Saudi Journal of Kidney Diseases and Transplantation, 2022 Burkholderia cepacia is almost always a colonizing organism rather than an infecting organism, but it may be pathogenic in immunocompromised individuals when isolated from body fluids that are ordinarily sterile.
Vijoy Kumar Jha +3 more
doaj +4 more sources
Gene expression profiling of Burkholderia cenocepacia at the time of cepacia syndrome: loss of motility as a marker of poor prognosis? [PDF]
Journal of Clinical Microbiology, 2015 ABSTRACT Cepacia syndrome (CS) is a fatal septic condition that develops in approximately 20% of cystic fibrosis (CF) patients chronically infected with the Burkholderia cepacia complex (Bcc). The most common causative agent is Burkholderia cenocepacia , a clinically dominant Bcc ...
Michal Kolář +2 more
exaly +5 more sources
Burkholderia cepacia meningitis in the Central African Republic [PDF]
The Pan African Medical Journal, 2019 Burkholderia cepacia causes frequent infections in immunocompromised and hospitalized patients, with a significant mortality rate. This bacterial species has also been associated with epidemic outbreaks due to contamination of antiseptic solutions and ...
Thierry Frank +7 more
doaj +2 more sources
Management of Cepacia Syndrome With a Combination of Intravenous and Inhaled Antimicrobials in a Non-Cystic Fibrosis Pediatric Patient. [PDF]
J Pediatr Pharmacol Ther, 2020 Burkholderia cepacia complex (Bcc) is an opportunistic pathogen, posing little risk to healthy individuals. The presentation of Bcc can vary from a virtually asymptomatic chronic infection, to an acute, life-threatening necrotizing pneumonia, acute respiratory distress syndrome, and bacteremia (cepacia syndrome) associated with a mortality ...
Branstetter JW, Yarbrough A, Poole C.
europepmc +4 more sources
A Case Report of Necrotizing Pneumonia Due to Burkholderia cepacia Syndrome. [PDF]
CureusBurkholderia cepacia (B. cepacia) complex is a highly resistant gram-negative pathogen known to cause lung infection in cystic fibrosis, chronic granulomatous disease, and immunocompromised patients. However, it may rarely infect immunocompetent patients as well.
Hedary AS, DeBord NL, Marshall D.
europepmc +3 more sources
Macrophage activation syndrome/haemophagocytic lymphohistiocytosis secondary to Burkholderia cepacia complex septicaemia in an elderly female carrier of X-linked chronic granulomatous disease with extreme lyonisation: 'cepacia syndrome' revisited. [PDF]
BMJ Case Rep, 2019 X-linked carriers of chronic granulomatous disease (CGD) may become phenotypically affected if substantial skewing from lyonisation occurs. We describe a 73-year-old female carrier with an overt CGD phenotype due to skewed lyonisation, complicated by macrophage activation syndrome (MAS)/haemophagocytic lymphohistiocytosis (HLH) secondary to ...
Urriola N, Williams A, Keat K.
europepmc +4 more sources
Community Acquired Burkholderia cepacia Bacteraemia Presenting as MODS in an Immunocompetent Individual: An Unusual Case [PDF]
Journal of Clinical and Diagnostic Research, 2017 Burkholderia cepacia has been recognized as a group of highly virulent organisms known as Burkholderia cepacia complex (Bcc). Bcc are ubiquitous in nature and most commonly found in moist environment, on plant roots and soil.
Ritesh Ranjan +2 more
doaj +1 more source
Genomic Insights into a New Burkholderia cenocepacia Sequence Type Linked to Cepacia Syndrome in Cystic Fibrosis. [PDF]
Curr MicrobiolAbstract Burkholderia cenocepacia is an important pathogen in cystic fibrosis (CF) patients, responsible for chronic lung infections and, in severe cases, cepacia syndrome (CS), characterized by necrotizing pneumonia, bacteremia, and high mortality. Epidemic lineages, such as
Xavier TS +8 more
europepmc +2 more sources
Clinicomicrobiological Profile and Antibiotic Susceptibility Pattern of Burkholderia cepacia Complex Isolates from a Tertiary Care Hospital in Southern India: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Burkholderia cepacia Complex (BCC) is a group of Gram negative betaproteobacteria with complex taxonomy that causes healthcare-associated infections and hospital outbreaks.
SUJA STAR PADMA +2 more
doaj +1 more source