Results 81 to 90 of about 4,670 (155)

Lung ultrasound evaluation in people with cystic fibrosis: A new approach in the pulmonology outpatient clinic

Pediatric Pulmonology, Volume 59, Issue 3, Page 592-599, March 2024.
Abstract Background Cystic fibrosis (CF) is a genetic disease that causes progressive lung disease with major impact on the quality of life. Lung ultrasound (LUS) allows to assess the lung involvement through the artefacts analysis and is increasingly used in children but is not yet used to monitor people with CF(pwCF).
Antonietta Curatola, Federica Corona, Domenica Squillaci, Alessia Saccari, Antonio Chiaretti, Egidio Barbi, Massimo Maschio   +6 more
wiley   +1 more source

THE MICROBIOTA OF LOWER AIRWAYS IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASES

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. We aimed to estimate the composition and the detection frequency of bacterial species in induced sputum samples from patients with bronchial asthma (BA), chronic obstructive lung disease (COPD) and its combined phenotype (ACOS).
S. A. Mazurina, G. A. Danilina, M. Yu. Smirnova, G. L. Osipova, V. B. Gervazieva, A. Yu. Konischeva, T. P. Ospelnikova   +6 more
doaj   +1 more source

Efek Ekstrak Etanol Daun Kemangi (Ocimum Sanctum) Sebagai Penghambat Pembentukan Biofilm Burkholderia Cepacia Secara In Vitro [PDF]

, 2017
Burkholderia cepacia merupakan salah satu bakteri patogen oportunistik yang membentuk biofilm yang sering menyebabkan pneumonia pada pasien dengan kondisi immunocompromised, termasuk pasien cystic fibrosis.
Lalitya, Wandira
core  

The mechanism of action of auranofin analogs in B. cenocepacia revealed by chemogenomic profiling

Microbiology Spectrum
Drug repurposing efforts led to the discovery of bactericidal activity in auranofin, a gold-containing drug used to treat rheumatoid arthritis. Auranofin kills Gram-positive bacteria by inhibiting thioredoxin reductase, an enzyme that scavenges reactive ...
Dustin T. Maydaniuk, Brielle Martens, Sarah Iqbal, Andrew M. Hogan, Neil Lorente Cobo, Anna Motnenko, Dang Truong, Sajani H. Liyanage, Mingdi Yan, Gerd Prehna, Silvia T. Cardona   +10 more
doaj   +1 more source

Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model

Frontiers in Microbiology, 2018
A Burkholderia cenocepacia infection usually leads to reduced survival and fatal cepacia syndrome in cystic fibrosis patients. The identification of B. cenocepacia essential genes for in vivo survival is key to designing new anti-infectives therapies. We
Yee-Chin Wong, Moataz Abd El Ghany, Moataz Abd El Ghany, Raeece N. M. Ghazzali, Soon-Joo Yap, Chee-Choong Hoh, Arnab Pain, Sheila Nathan   +7 more
doaj   +1 more source

Low iron-induced small RNA BrrF regulates central metabolism and oxidative stress responses in Burkholderia cenocepacia.

PLoS ONE, 2020
Regulatory small RNAs play an essential role in maintaining cell homeostasis in bacteria in response to environmental stresses such as iron starvation.
Andrea M Sass, Tom Coenye
doaj   +1 more source

Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation

Journal of Bacteriology
Phenotypic diversity in bacteria often results from adaptation to changing environmental conditions, exemplified by variable colony morphotypes. In Burkholderia pseudomallei, discrete genomic alterations and modulation of gene expression facilitate ...
Pauline M. L. Coulon, Marie-Christine Groleau, Abderrahman Hachani, Matthew P. Padula, Timothy P. Stinear, Eric Déziel   +5 more
doaj   +1 more source

Candidate essential genes in Burkholderia cenocepacia J2315 identified by genome-wide TraDIS

Frontiers in Microbiology, 2016
Burkholderia cenocepacia infection often leads to fatal cepacia syndrome in cystic fibrosis patients. However, antibiotic therapy rarely results in complete eradication of the pathogen due to its intrinsic resistance to many clinically available ...
Yee-Chin Wong, Moataz Abd El Ghany, Raeec Naeem, Kok-Wei lee, Yung-Chie Tan, Arnab Pain, Sheila Nathan   +6 more
doaj   +1 more source

In vitro resistance of Burkholderia cepacia complex isolates to reactive oxygen species in relation to catalase and superoxide dismutase production

, 2001
The Burkholderia cepacia complex comprises groups of genomovars (genotypically distinct strains with very similar phenotypes) that have emerged as important opportunistic pathogens in cystic fibrosis (CF) patients.
Miguel A. Valvano, Lefebre, M, Valvano, M; id_orcid, Matthew D. Lefebre   +3 more
core   +1 more source

Syndrome d’activation lymphohistiocytaire associé à une infection à Burkholderia cepacia complex chez un nourrisson révélant une granulomatose septique et une intégration génomique du virus HHV-6 [Lymphohistiocytic activation syndrome and Burkholderia cepacia complex infection in a child revealing chronic granulomatous disease and chromosomal integration of the HHV-6 genome].

, 2011
International audienceChronic granulomatous disease (GCD) is characterized by severe infections, notably with Burkholderia cepacia complex (BCC). GCD is rarely complicated by lymphohistiocytic activation syndromes, most often secondary to bacterial or ...
A. Araujo, Plantaz, D., A. Pagnier, Pagnier, A., Wroblewski, I., Morand, Philippe, Stasia, M.-J., D. Plantaz, M.-J. Stasia, Araujo, A., I. Wroblewski, Frange, P., P. Frange, P. Morand   +13 more
core   +1 more source