Results 41 to 50 of about 177,089 (78)

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2

Molecules and Cells, 2019
SUMMARY Proximity-dependent biotin labeling (BioID) may identify new targets for cancers driven by difficult-to-drug oncogenes, such as Ras. Therefore, BioID was used with wild-type (WT) and oncogenic mutant (MT) H-, K-, and N-Ras, identifying known ...
Joanna R Kovalski, A. Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Y. Che, Glenn G. Wozniak, P. Khavari   +6 more
semanticscholar   +1 more source

Ethiopian vegetation types, climate and topography. [PDF]

Plant Divers, 2020
Asefa M, Cao M, He Y, Mekonnen E, Song X, Yang J.   +5 more
europepmc   +1 more source

The Forest Observation System, building a global reference dataset for remote sensing of forest biomass. [PDF]

Sci Data, 2019
Schepaschenko D, Chave J, Phillips OL, Lewis SL, Davies SJ, Réjou-Méchain M, Sist P, Scipal K, Perger C, Herault B, Labrière N, Hofhansl F, Affum-Baffoe K, Aleinikov A, Alonso A, Amani C, Araujo-Murakami A, Armston J, Arroyo L, Ascarrunz N, Azevedo C, Baker T, Bałazy R, Bedeau C, Berry N, Bilous AM, Bilous SY, Bissiengou P, Blanc L, Bobkova KS, Braslavskaya T, Brienen R, Burslem DFRP, Condit R, Cuni-Sanchez A, Danilina D, Del Castillo Torres D, Derroire G, Descroix L, Sotta ED, d'Oliveira MVN, Dresel C, Erwin T, Evdokimenko MD, Falck J, Feldpausch TR, Foli EG, Foster R, Fritz S, Garcia-Abril AD, Gornov A, Gornova M, Gothard-Bassébé E, Gourlet-Fleury S, Guedes M, Hamer KC, Susanty FH, Higuchi N, Coronado ENH, Hubau W, Hubbell S, Ilstedt U, Ivanov VV, Kanashiro M, Karlsson A, Karminov VN, Killeen T, Koffi JK, Konovalova M, Kraxner F, Krejza J, Krisnawati H, Krivobokov LV, Kuznetsov MA, Lakyda I, Lakyda PI, Licona JC, Lucas RM, Lukina N, Lussetti D, Malhi Y, Manzanera JA, Marimon B, Junior BHM, Martinez RV, Martynenko OV, Matsala M, Matyashuk RK, Mazzei L, Memiaghe H, Mendoza C, Mendoza AM, Moroziuk OV, Mukhortova L, Musa S, Nazimova DI, Okuda T, Oliveira LC, Ontikov PV, Osipov AF, Pietsch S, Playfair M, Poulsen J, Radchenko VG, Rodney K, Rozak AH, Ruschel A, Rutishauser E, See L, Shchepashchenko M, Shevchenko N, Shvidenko A, Silveira M, Singh J, Sonké B, Souza C, Stereńczak K, Stonozhenko L, Sullivan MJP, Szatniewska J, Taedoumg H, Ter Steege H, Tikhonova E, Toledo M, Trefilova OV, Valbuena R, Gamarra LV, Vasiliev S, Vedrova EF, Verhovets SV, Vidal E, Vladimirova NA, Vleminckx J, Vos VA, Vozmitel FK, Wanek W, West TAP, Woell H, Woods JT, Wortel V, Yamada T, Nur Hajar ZS, Zo-Bi IC.   +142 more
europepmc   +1 more source

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.

Cell, 1997
M. Serrano, Athena W. Lin, M. McCurrach, D. Beach, D. Beach, S. Lowe   +5 more
semanticscholar   +1 more source

RAS is regulated by the let-7 microRNA family.

Cell, 2005
Steven M. Johnson, H. Grosshans, Jaclyn Shingara, M. Byrom, R. Jarvis, Angie Cheng, E. Labourier, Kristy L. Reinert, D. Brown, F. Slack   +9 more
semanticscholar   +1 more source

RAS isoforms and mutations in cancer at a glance

Journal of Cell Science, 2016
G. A. Hobbs, C. Der, K. Rossman
semanticscholar   +1 more source

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

New England Journal of Medicine, 2008
C. Karapetis, S. Khambata-Ford, D. Jonker, C. O'Callaghan, D. Tu, N. Tebbutt, R. Simes, H. Chalchal, J. Shapiro, S. Robitaille, T. Price, L. Shepherd, H. Au, C. Langer, M. Moore, J. Zalcberg   +15 more
semanticscholar   +1 more source

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer.

New England Journal of Medicine, 2013
J. Douillard, K. Oliner, S. Siena, J. Tabernero, R. Burkes, M. Barugel, Y. Humblet, G. Bodoky, D. Cunningham, J. Jassem, F. Rivera, I. Kocáková, P. Ruff, M. Błasińska-Morawiec, M. Šmakal, J. Canon, M. Rother, R. Williams, Alan Rong, J. Wiezorek, R. Sidhu, S. Patterson   +21 more
semanticscholar   +1 more source

Drugging RAS: Know the enemy

Science, 2017
Bjoern Papke, C. Der
semanticscholar   +1 more source

RAS-targeted therapies: is the undruggable drugged?

Nature Reviews Drug Discovery, 2020
RAS (KRAS, NRAS and HRAS) is the most frequently mutated gene family in cancers, and, consequently, investigators have sought an effective RAS inhibitor for more than three decades.
Amanda R Moore, Frank Mccormick, Shiva Malek   +2 more
exaly   +2 more sources