Results 111 to 120 of about 137,963 (330)
ABSTRACT Siderophore cephalosporins are designed to exploit bacterial nutrient uptake systems to gain accelerated uptake across the outer membrane of Gram-negative bacteria. They contain iron (III) binding motifs that allow them to form complexes that will be recognized as potential substrates
openaire +2 more sources
Evolution of an acylase active on cephalosporin C [PDF]
Semisynthetic cephalosporins are synthesized from 7-amino cephalosporanic acid, which is produced by chemical deacylation or by a two-step enzymatic process of the natural antibiotic cephalosporin C.
Walter Cabri +23 more
core +1 more source
Abstract Objectives Biliary atresia (BA) is a cholangiopathy characterized by obstruction of the intrahepatic and extrahepatic bile ducts. Hepatic portoenterostomy (HPE) is the primary palliative treatment and there is still an urgent need to improve post‐HPE management.
Bianca Ferraz de Almeida Silva +7 more
wiley +1 more source
This study assesses the synergistic effect of the combination of cephalosporins and sulbactam with daptomycin against daptomycin-nonsusceptible, vancomycin-intermediate resistant Staphylococcus aureus (VISA) or heterogeneous vancomycin-intermediate S ...
Chih-Cheng Lai +8 more
doaj +1 more source
BACKGROUND Spontaneous bacterial peritonitis (SBP) is the most prevalent bacterial infection in patients with cirrhosis. Although studies from Europe have reported significant rates of resistance to third-generation cephalosporins, there are limited SBP ...
Jennifer Chaulk +7 more
semanticscholar +1 more source
Enzymes with cephalosporin C acyalse activity obtained by site-directed, random or "site-saturation" mutagenesis of a native sequence optimized for expression in E ...
CUCCHETTI E +5 more
core
Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato +2 more
wiley +1 more source
Objective: The objective of this review is to describe the outcomes of patients treated with ceftaroline in the non-Food and Drug Administration (FDA) approved indication of methicillin-resistant Staphylococcus aureus (MRSA) infections in both pediatric ...
Nicole Lounsbury +3 more
doaj +1 more source
In the fernientalion of cephalosporin C (CPC) using a mutant strain, Cephaiosporium acremonium M-l 13, CPC was converted into deacetyl cephalosporin C (DCPC) by cephalosporin C acetyl hydrolase (CAH). After complete consumption of glucose in fermentation
Yung Hee Kho +3 more
core
Nail Surgery in Children: Specific Challenges and Practical Considerations
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley +1 more source

