Results 1 to 10 of about 117,600 (325)

Cephalosporins as key lead generation beta-lactam antibiotics

Applied Microbiology and Biotechnology, 2022
Antibiotics are antibacterial compounds that interfere with bacterial growth, without harming the infected eukaryotic host. Among the clinical agents, beta-lactams play a major role in treating infected humans and animals.
Xuemei Lin, U. Kück
exaly   +2 more sources

Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000–2013

Journal of Infectious Diseases, 2016
Background. Treatment of Neisseria gonorrhoeae infection is empirical and based on population-wide susceptibilities. Increasing antimicrobial resistance underscores the potential importance of rapid diagnostic tests, including sequence-based tests, to ...
Yonatan H Grad, Simon Harris, Anna G Green   +2 more
exaly   +2 more sources

Cephalosporins: A Focus on Side Chains and β-Lactam Cross-Reactivity

Pharmacy (Basel, Switzerland), 2019
Cephalosporins are among the most commonly prescribed antibiotic classes due to their wide clinical utility and general tolerability, with approximately 1–3% of the population reporting a cephalosporin allergy.
Michael P Veve, Jamie L Wagner
exaly   +2 more sources

Characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli obtained from Danish pigs, pig farmers and their families from farms with high or no consumption of third- or fourth-generation cephalosporins

Journal of Antimicrobial Chemotherapy, 2014
Anette M Hammerum, Jesper Larsen, Frank M Aarestrup   +2 more
exaly   +2 more sources

Stevens-Johnson syndrome: a case report of possible cephalosporin-induced cutaneous adverse reaction

Journal of Infection in Developing Countries, 2023
A severe medical condition known as Stevens-Johnson syndrome (SJS) is marked by a cutaneous and mucosal reaction from the use of specific medications. The prodromal illness is followed by severe mucocutaneous symptoms in this immune-mediated disease. We
Anna Mkhoyan, Md. Foorquan Hashmi, Fiza Khan, Naira Gyulazyan, Vigen Asoyan, Varsen Nersisyan   +5 more
doaj   +1 more source

Intestinal Exposure to Ceftiofur and Cefquinome after Intramuscular Treatment and the Impact of Ceftiofur on the Pig Fecal Microbiome and Resistome

Antibiotics, 2022
Optimization of antimicrobial treatment during a bacterial infection in livestock requires in-depth knowledge of the impact of antimicrobial therapy on the pathogen and commensal microbiota.
Sofie Rutjens, Nick Vereecke, Ward De Spiegelaere, Siska Croubels, Mathias Devreese   +4 more
doaj   +1 more source

Consumption of cephalosporins in the community, European Union/European Economic Area, 1997–2017

Journal of Antimicrobial Chemotherapy, 2021
Objectives Data on cephalosporin consumption in the community were collected from 30 EU/EEA countries over two decades. This article reviews temporal trends, seasonal variation, presence of change-points and changes in the composition of the main ...
A. Versporten, R. Bruyndonckx, N. Adriaenssens, N. Hens, D. Monnet, G. Molenberghs, H. Goossens, K. Weist, S. Coenen   +8 more
semanticscholar   +1 more source

Oral Cephalosporins [PDF]

Journal of Antimicrobial Chemotherapy, 1992
The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections.
J, Verhaegen, L, Verbist
openaire   +4 more sources

Extended-spectrum beta-lactamases producing extensively drug-resistant Salmonella Typhi in Punjab, Pakistan

Journal of Infection in Developing Countries, 2020
Introduction: The multidrug-resistant (MDR) Salmonella enterica serovar Typhi isolates have been increasingly reported from the Asian and African countries.
Muhammad Saeed, Muhammad Hidayat Rasool, Farhan Rasheed, Muhammad Saqalein, Muhammad Atif Nisar, Ambreen Anwar Imran, Saba Tariq, Afreenish Amir, Aamer Ikram, Mohsin Khurshid   +9 more
doaj   +1 more source

Co-production of ESBL and AmpC β-Lactamases in Clinical Isolates of A. baumannii and A. lwoffii in a Tertiary Care Hospital From Northern India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Acinetobacter baumannii is an important cause of health care associated infections which are difficult to control and treat, because of widespread antimicrobial resistance which is possessed by this organism.
Pooja Singla, Rama Sikka, Antariksh Deeep, Deep Gagneja, Uma Chaudhary   +4 more
doaj   +1 more source