Results 151 to 160 of about 81,013 (301)

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3874-3885, November 2026.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Microbial oxidation of cephalosporins to cephalosporin sulfoxides.

Agricultural and Biological Chemistry, 1980
TORII, Hiroshi, ASANO, Tsuneo, MATSUMOTO, Norichika, KATO, Koichi, TSUSHIMA, Susumu, KAKINUMA, Atsushi   +5 more
openaire   +2 more sources

Theoretical studies on Beta-lactam antibiotics VI: Conformational analysis and structure-activity relationships of penicillin sulfoxides and cephalosporins

, 1982
Conformational energy calculations were carried out on penicillin α-and Β-sulfoxides and δ2- and δ3-cephalosporins, in order to identify the structural features governing their biological activity.
Joshi, NV, Rao, VSR
core  

Biosynthetic Pathways and Regulation of Antibacterial Compounds From Endophytic Fungi: From Chemistry to Genomics and Biotechnology

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Endophytic fungi encode abundant cryptic biosynthetic gene clusters that remain largely silent under conventional cultivation. This review highlights how genome mining, multi‐omics, and cluster activation strategies bridge the BGC‐to‐metabolite gap, enabling the discovery of structurally diverse antibacterial natural products with activity against ...
Farkhod Eshboev, Abubakar Siddiq Salihu, Lobar Khayrullaeva, Doniyor Khamdamov, Alex X. Gao, Kamila Mardieva, Wan Mohd Nuzul Hakimi Wan Salleh, Shakhnoz Azimova, Karl W. K. Tsim   +8 more
wiley   +1 more source

Rapid Progression of Acute Acalculous Cholecystitis to Gangrenous Cholecystitis in an Initially Non‐Critically Ill Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Acute acalculous cholecystitis (AAC) is not confined to the critically ill and may behave like calculous disease. A 65‐year‐old hypertensive man with localized, stone‐free cholecystitis deteriorated on hospital Day 4 with peritonism, acidosis, and acute kidney injury.
Rami Y. Adam, Sami J. Eldein, Mahmoud M. Mahmoud, Mohamed S. M. Elshikhawoda, Omer Musa, Faris Abdon   +5 more
wiley   +1 more source

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie, Ermias Endewunetu, Yosef Temesgen, Demissew Shenkute Gebreyes, Zenawork Sahile, Biniam Mekonnen, Getachew Bizuneh, Asrat Berihun, Berhanu Yitayew   +8 more
wiley   +1 more source

Microbiological Spectrum and Antimicrobial Resistance Patterns in Tubo‐Ovarian Abscesses Managed by Surgery or Drainage at a Tertiary Hospital in Vietnam: A Retrospective Case Series

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Tubo‐ovarian abscess requires empirical antimicrobial therapy before culture results are available, but local antimicrobial resistance data are limited in Vietnam. We described the microbiological spectrum and antimicrobial susceptibility patterns of tubo‐ovarian abscesses managed by surgery or drainage.
Bui Chi Thuong, Huynh Tan An, Pham Dinh Nguyen   +2 more
wiley   +1 more source

Impact of COVID‐19 Restrictions on Estimating Causal Effects: Fluoroquinolones and Tendon Rupture

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose The COVID‐19 pandemic disrupted healthcare services, potentially affecting causal effect estimation using real‐world data. As a case study, we replicated a cohort study using Clinical Practice Research Datalink Aurum to evaluate whether pandemic‐related disruptions influenced the measured association between fluoroquinolone use and ...
Angel Y. S. Wong, Jeremy P. Brown, John Tazare, Marleen Bokern, Elizabeth Williamson, Jonathan Bartlett, Charlotte Warren‐Gash, Ian Douglas   +7 more
wiley   +1 more source

Engineering Safety Through MOFs‐Based Nanocomposites: Advances in Design, Fabrication, and Deployment Across Emerging Domains

Rare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Ensuring uncompromised safety across interconnected domains is vital for global societal sustainability. Metal–organic framework (MOF)‐based nanocomposites, owing to their intrinsically tunable structures and broad functional versatility, represent a powerful class of materials for safety‐related engineering.
Rongfu Peng, Chong Chen, Hao Yang, Quan Lou, Yiju Tang, Dongwei Zhu, Chengzhang Zhu   +6 more
wiley   +1 more source

Molecular Characterisation and Antimicrobial Resistance Patterns of Listeria monocytogenes From Dairy Sources

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
This study presents a comprehensive surveillance of L. monocytogenes along the dairy supply chain, from raw milk collection to final products and environmental sources. The methodological framework encompasses conventional microbiological isolation and identification, followed by phenotypic antimicrobial susceptibility testing and calculation of the ...
Mohammad Reza Heidari, Amir Shakerian, Reza Sharafati Chaleshtori, Ebrahim Rahimi   +3 more
wiley   +1 more source