Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]
, 2009 The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa +5 more
core +1 more source
Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review
JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky +6 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Chronic otitis media (COM) is a major public health concern, particularly in developing countries. Although complications have decreased with modern antibiotics, they still cause significant morbidity and mortality. This study analyzed the clinical features, bacteriological profiles, and treatment outcomes of COM complications at a ...
Viraporn Atchariyasathian +1 more
wiley +1 more source
Long‐Term Results of UPPP and Coblation Channeling of the Tongue for Obstructive Sleep Apnea
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective To evaluate the long‐term surgical outcomes of combined uvulopalatopharyngoplasty (UPPP) and coblation channeling of the tongue (CCT) for moderate‐to‐severe obstructive sleep apnea (OSA). Methods The study enrolled patients with moderate‐to‐severe OSA who underwent treatment with UPPP plus CCT and had a minimal follow‐up of 2 years ...
Ren‐Hui Chen +3 more
wiley +1 more source
Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]
, 2016 This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon +15 more
core
Active Emergency Management of Adult Acute Epiglottitis: An Analysis of 570 Cases
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Acute epiglottitis, which is primarily caused by bacterial infection, can quickly progress to life‐threatening airway obstruction. The first 24 h after symptom onset is a critical window for management. However, few studies have evaluated the effect of emergency management during this period or have identified the factors that ...
Bo‐Jun Shen +7 more
wiley +1 more source
Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]
, 2017 Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core +1 more source
Bacteraemia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features [PDF]
, 2010 A. Courpon-Claudinon +9 more
openalex +1 more source
Microbiology and Immunology, EarlyView.ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Carlos Henrique Camargo +21 more
wiley +1 more source