Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair +3 more
wiley +1 more source
Observed and Forecasted Antibiotic Consumption by ATC/DDD Metrics: A Real-World Modeling Study with Implications for Antimicrobial Stewardship. [PDF]
Bekyarov P, Lambev M, Mihaylova S.
europepmc +1 more source
Pathogenesis of bacterial diseases in Nile tilapia and anti‐bacterial mechanisms. ABSTRACT Nile tilapia (Oreochromis niloticus) is among the most widely farmed fish globally that plays a major role in ensuring food security in many low‐ and middle‐income countries.
Catherine Agoe +8 more
wiley +1 more source
Orbital Tuning of the β-Lactam Warhead: Intrinsic n → π* Preactivation in Cephalosporins. [PDF]
Mato S +4 more
europepmc +1 more source
Applying machine learning to pharmacovigilance data: A proof‐of‐concept study
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus +6 more
wiley +1 more source
Epidemiological features and antibiotic resistance of <i>Salmonella</i> strains isolated from diarrheal cases in Gansu Province, China, 2024. [PDF]
Lan G +5 more
europepmc +1 more source
ABSTRACT In this pediatric brain abscess case, metagenomic next‐generation sequencing (mNGS) identified an anaerobic bacterium that remained undetected using conventional culture methods, thus providing clinically relevant information for antimicrobial management. This indicates that mNGS may be a useful adjunct for optimizing treatment strategies.
Risa Nagase +9 more
wiley +1 more source
Comparative effectiveness of levofloxacin versus third-generation cephalosporins and predictors of treatment outcomes in upper respiratory tract scleroma: a tertiary center experience. [PDF]
Khaleel AI +3 more
europepmc +1 more source
Weil's Syndrome Masquerading as Acute Cholangitis: A Case Report of a Farmer With Leptospirosis
ABSTRACT Leptospirosis can masquerade as acute cholangitis with cholestatic jaundice, fever, and leukocytosis. In febrile patients with cholestatic liver profile without biliary obstruction, especially farmers with calf pain and conjunctival suffusion, consider leptospirosis early to initiate timely antibiotics and prevent poor outcomes.
Ahmed Ali Shaikh +5 more
wiley +1 more source
Gentamicin and antibiotic use in Norwegian hospitals: a study from 35 point-prevalence surveys, 2015 to 2023. [PDF]
Vuković M +6 more
europepmc +1 more source

