Results 191 to 200 of about 73,761 (291)

Evaluating the Risk of Coagulopathy in Cephalosporins with Different Side Chains: A Propensity Score-Weighted Study. [PDF]

Medicina (Kaunas)
Tai CH, Liang FW, Lee CH.
europepmc   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

Antibiotic Resistance Profile of Wound Infection Isolates: High Resistance to Cephalosporins and Penicillin Among Ghanaian Patients in a Cross-Sectional Study. [PDF]

Health Sci Rep
Kwashie N, Antwi-Baffour S, Annison L, Appah LO, Paul U, Akpobi S, Senu E.   +6 more
europepmc   +1 more source

Global Distribution and Comparative Resistance Profiles of Escherichia coli Isolated From Bovine Meat and Meat Products: Evidence From Network Meta‐Analysis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Schematic overview of the study and its principal findings. E. coli isolated from bovine meat and meat products was evaluated for antimicrobial resistance using Bayesian network meta‐analysis. The graphical abstract highlights the antimicrobial resistance ranking based on SUCRA, showing high resistance to penicillin, doxycycline, amoxicillin ...
Yaser Khorram Del, Peyman Mahmoudi, Amir Rashidi, Skala Idrees Hama Faraj, Jalal Rostamzadeh, Mohammad Razmkabir   +5 more
wiley   +1 more source

Appropriateness and Abuse of Antipyretics, Anti-Inflammatory Drugs and Antibiotics in Children and Adults. [PDF]

Antibiotics (Basel)
Nicolini G, Crapis M, Lo Vecchio A, SITIP, Parrella R, SIMIT.   +5 more
europepmc   +1 more source

Trends in Enterobacteriaceae Resistance Patterns: A Nine‐Year Retrospective Study From North Lebanon

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Antimicrobial resistance (AMR) in Enterobacteriaceae poses a critical threat to global health, particularly in regions where antibiotic misuse and limited surveillance prevail. Intensive care units (ICUs) act as focal points for resistance emergence and dissemination. This study aimed to evaluate long‐term resistance trends
Mazen Zaylaa, Maya El Bitar, Ali Jaafar, Majd Hammoud, Hiba El Chakra, Abdul Rahman Maaliki, Farah El Dali, Dina Awad, Yasmine Hijazi, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Diala Wehbe   +12 more
wiley   +1 more source

Correction: Korytkowski et al. Luminescence-Based Strategies for Detecting β-Lactamase Activity: A Review of the Last Decade. <i>Life</i> 2026, <i>16</i>, 250. [PDF]

Life (Basel)
Korytkowski MJ, Baraniak A, Boryło A, Rudnicki-Velasquez P.   +3 more
europepmc   +1 more source

Incidence, Mortality, and Determinants of Ventilator‐Associated Pneumonia Among Pediatric Patients at the National Referral Hospital, Bhutan: A Prospective Cohort Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Ventilator‐associated pneumonia (VAP) is a common healthcare‐associated infection in pediatric intensive care units (PICUs). In Bhutan, baseline data on VAP are limited. This study aimed to determine the incidence, mortality, and factors associated with VAP among mechanically ventilated pediatric patients at the Jigme Dorji ...
Tashi Tshering, Yeshey Dorjey, Kuenley Pedon, Mimi Lhamu Mynak   +3 more
wiley   +1 more source

Correction: Repurposing cephalosporins as excellent anticancer agents and chemosensitizers for inflammation-driven cancer therapy. [PDF]

Sci Rep
Liu N, Cao W, Tang J, Dong R, Guo J, Luo Z, Yao Q, Teng S, Liang Z, Yang Y, Gu M, Zhou J, Chen W, Liang H, He X.   +14 more
europepmc   +1 more source