Results 41 to 50 of about 110,179 (326)

Oral flora of domestic cats in Hong Kong: Identification of antibiotic‐resistant strains

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 25-36, January 2023., 2023
Abstract Background As the clinical outcome of bite‐associated infection is related to the oral commensals, evaluating their composition and antibiotic susceptibility pattern can provide more information for the antibiotic treatment of wound infections and increase the awareness of the multidrug‐resistant bacteria in cat oral flora. Aims This study was
Ka Tik Cheung, Hau Yan Chan
wiley   +1 more source

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis

open access: yesJournal of Medicinal Chemistry, 2016
We report two series of novel cephalosporins that are bactericidal to Mycobacterium tuberculosis alone of the pathogens tested, which only kill M. tuberculosis when its replication is halted by conditions resembling those believed to pertain in the host,
B. Gold   +20 more
semanticscholar   +1 more source

Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to Enterobacter, Serratia, and Citrobacter Species

open access: yesAntibiotics, 2020
Objectives: There is debate on whether the use of third-generation cephalosporins (3GC) increases the risk of clinical failure in bloodstream infections (BSIs) caused by chromosomally-mediated AmpC-producing Enterobacterales (CAE).
Caroline Derrick   +21 more
doaj   +1 more source

Major Aspects of Detection and Monitoring of Adverse Reactions Associated with Cephalosporin Antibiotic Treatment

open access: yesБезопасность и риск фармакотерапии, 2021
Widespread use of cephalosporin antibiotics in clinical practice calls for greater attention to the risk of adverse drug reactions. Information on serious or unexpected adverse events reported during post-marketing experience is submitted to national and
E. Yu. Demchenkova   +7 more
doaj   +1 more source

Oral Cephalosporins [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 1992
The arrival of new cephalosporins faces the clinician with an evergrowing confusion as to the drug of choice. The older agents (cephalexin, cephradine, cefadroxil and cefaclor) and the newer formulations cefatrizine and cefuroxime axetil are intensively used for treatment of mild and moderate infections.
J, Verhaegen, L, Verbist
openaire   +4 more sources

Molecular Identification of TEM and SHV Genes in Extended Spectrum Beta-lactamase Producing Escherichia coli and Klebsiellae pneumoniae Isolates in a Tertiary Care Hospital, Bangladesh

open access: yesJournal of Pure and Applied Microbiology, 2017
Extended spectrum b-lactamases (ESBLs) are enzymes encoded by mutation of a class of genes such as TEM, SHV, OXA and CTX etc. in gram negative Enterobacteriaceae.
Md. Hasanul Karim   +2 more
doaj   +1 more source

Use of Hypoprothrombinemia-Inducing Cephalosporins and the Risk of Hemorrhagic Events: A Nationwide Nested Case-Control Study

open access: yesPLoS ONE, 2016
Objective Existing data regarding the risk of hemorrhagic events associated with exposure to hypoprothrombinemia-inducing cephalosporins are limited by the small sample size.
Li-Ju Chen   +6 more
semanticscholar   +1 more source

Cefazolin remains the linchpin for preventing acute periprosthetic joint infection following primary total knee arthroplasty

open access: yesBone & Joint Open, 2022
Aims: Despite recent literature questioning their use, vancomycin and clindamycin often substitute cefazolin as the preoperative antibiotic prophylaxis in primary total knee arthroplasty (TKA), especially in the setting of documented allergy to ...
Daniel B. Buchalter   +5 more
doaj   +1 more source

Hydrolysis of Cephalexin and Meropenem by New Delhi Metallo $β$-Lactamase: Substrate Protonation Mechanism is Drug Dependent [PDF]

open access: yes, 2017
Emergence of antibiotic resistance due to New Delhi Metallo $\beta$-lactamase (NDM-1) bacterial enzymes is of great concern due to their ability to hydrolyze wide range of antibiotics. Efforts are ongoing to obtain the atomistic details of the hydrolysis mechanism in order to develop novel drugs and inhibitors against NDM-1.
arxiv   +1 more source

Trends in Neisseria gonorrhoeae Susceptibility to Cephalosporins in the United States, 2006-2014.

open access: yesJournal of the American Medical Association (JAMA), 2015
Gonorrhea is a common sexually transmitted disease that, if untreated, can cause reproductive health complications. Gonorrhea treatment has been repeatedly jeopardized by antimicrobial resistance.
R. Kirkcaldy   +6 more
semanticscholar   +1 more source

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