Results 41 to 50 of about 149,559 (362)
Molecules, 2012 New derivatives of 7-aminocephalosporanic acid 1–8 were synthesized by acylation of the 7-amino group of the cephem nucleus with various arylidinimino-1,3,4-thiadiazole-thio(or dithio)-acetic acid intermediates 3a–d and 5a–d, respectively, so the acyl ...
Shakir Mahmood Alwan
doaj +1 more source
PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance. [PDF]
, 2018 β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Chambers, Henry F +3 more
core +3 more sources
Repurposing clinically approved cephalosporins for tuberculosis therapy
Scientific Reports, 2016 While modern cephalosporins developed for broad spectrum antibacterial activities have never been pursued for tuberculosis (TB) therapy, we identified first generation cephalosporins having clinically relevant inhibitory concentrations, both alone and in
S. Ramón-García +9 more
semanticscholar +1 more source
Structural and Functional Aspects of Class A Carbapenemases. [PDF]
, 2016 The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core +2 more sources
Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]
, 2017 Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina +15 more
core +5 more sources
Role of cephalosporins in the era of Clostridium difficile infection
Journal of Antimicrobial Chemotherapy, 2016 The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since 2000. Previous meta-analyses have suggested a strong association between cephalosporin use and CDI, and many national programmes on CDI control have focused on ...
M. Wilcox +4 more
semanticscholar +1 more source
Veterinary Medicine and Science, Volume 9, Issue 1, Page 513-522, January 2023., 2023 The average isolation rate of livestock‐associated S. aureus is 6.5%, and the S. aureus isolates showed high resistance to a wide range of antimicrobials. Most strains, with the exception of three chicken‐associated strains, harbored blaTEM‐1a gene. All S.
Qingshuang Dong +5 more
wiley +1 more source
Antibiotics, 2020 Objectives: There is debate on whether the use of third-generation cephalosporins (3GC) increases the risk of clinical failure in bloodstream infections (BSIs) caused by chromosomally-mediated AmpC-producing Enterobacterales (CAE).
Caroline Derrick +21 more
doaj +1 more source
Безопасность и риск фармакотерапии, 2021 Widespread use of cephalosporin antibiotics in clinical practice calls for greater attention to the risk of adverse drug reactions. Information on serious or unexpected adverse events reported during post-marketing experience is submitted to national and
E. Yu. Demchenkova +7 more
doaj +1 more source
Overview of the clinical features of cefixime [PDF]
, 1998 Third-generation cephalosporins in oral formulations have become an increasingly important first-line choice against common bacterial infections. Cefixime is one such agent, which possesses excellent efficacy against a broad spectrum of pathogens ...
Adam, Dieter
core +1 more source