Results 41 to 50 of about 159,979 (309)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Durum wheat and allelopathy: towards wheat breeding for natural weed management

open access: yesFrontiers in Plant Science, 2013
Wheat-derived foodstuffs represent about one-fifth of the calories consumed by humans worldwide. Bread wheat (Triticum aestivum L.) is one of the most important crops throughout the world, and it has been extensively studied for its allelopathic ...
Mariagiovanna eFragasso   +2 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

„Crucile de jurământ” din județul Gorj: simbolism și interpretare

open access: yesRevista de Etnologie şi Culturologie
Crucile de jurământ”, considerate conform tradiției ca „locul de odihnă al sufletelor” celor decedați sau „casa sufletului”, reprezintă un obicei unic în România, specific unor localități din județul Gorj, cum ar fi Hurezani, Licurici, Aninoasa ...
Dumitru-Cătălin Rogojanu   +1 more
doaj   +1 more source

Potential reproduction of invasive Asian carps (Hypophthalmichthys spp.) in Lake Balaton: pro and contra evidences

open access: yesFrontiers in Marine Science, 2015
Asian carps (bighead carp Hypophthalmichthys nobilis × silver carp H. molitrix) had been introduced into Lake Balaton (Hungary) from 1972 to increase fishery yields and as a biological control of algal blooms.
Attila Mozsár   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Analisis Kebutuhan Bimbingan Pribadi Sosial Berbasis Context, Experience, and Reality (CER) untuk Meningkatkan Karakter Kebajikan Siswa Sekolah Menengah Pertama

open access: yesJurnal Kajian Bimbingan dan Konseling, 2019
: The general objective of the study is to describe the needs of junior high school counselor toward CER-based socio-personal guidance service in order to improve the virtue of junior high school students.
IM Hambali
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Evans Library-Library Naming Cer. - 1

open access: yes, 2009
Evans Library-Library Naming ...
Unknown
core   +1 more source

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