Results 151 to 160 of about 72,817 (297)

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Ceramid [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Post‐Occlusion Application of Skin Protective Creams Does Not Affect Occlusion‐Induced Barrier Changes: A Randomized Controlled Experimental Study

Contact Dermatitis, EarlyView.
Post‐occlusion application of protective creams did not consistently reduce occlusion‐induced skin barrier impairment after glove use. Protective efficacy probably depends on formulation and timing, with only immediate pre‐irritant application showing a significant reduction in SLS‐induced barrier disruption.
Michal Gina, Katharina Wichert, Thomas Behrens, Thomas Brüning, Julia Krabbe   +4 more
wiley   +1 more source

Sphingolipid Metabolism in Obesity: Bidirectional Regulation and Comparative Perspectives on Plant Sphingolipids. [PDF]

Nutrients
Li M, Yao Y, Li T, Cai T, Zhao F, Fang Y, Zheng Y, Fei C, Yang C, Sun W, Shao M, Li L, Zheng Y.   +12 more
europepmc   +1 more source

Serum Lipidomics Profiling Identify Novel Biomarkers of Distal Symmetrical Polyneuropathy in Type 1 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk, Tina Okdahl, Marietta Kokla, Tommi Suvitaival, Gurjeet Kaur, Ismo M. Mattila, Simon M. Kienle, Christian Buhl, Knud Yderstræde, Troels S. Jensen, Peter Rossing, Flemming Pociot, Birgitte Brock, Cristina Legido‐Quigley, Páll Karlsson, Christian S. Hansen, Christina Brock, Joachim Størling, Karolina Sulek   +18 more
wiley   +1 more source

Sphingolipid Metabolism: A Pathological Hub Linking Lipid Dysregulation and Chronic Inflammation in Atherosclerotic Cardiovascular Disease. [PDF]

J Inflamm Res
Wang S, Dong Y, Li X, Dong R, Jing L.
europepmc   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

Ceramide-Induced Endoplasmic Reticulum Stress Reveals a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer. [PDF]

Mol Cancer Res
Pal P, Chitkara S, Sarpey GK, Vashi A, Rawat V, Alani F, Zhao H, Ata M, Qu J, Schiff R, Tonetti D, Greene GL, Frasor J, Atilla-Gokcumen GE, Coloff JL.   +14 more
europepmc   +1 more source

A serum and cream moisturization regimen outperforms separate use in sustaining hydration, reducing TEWL, and balancing surface lipids over an 8‐h study

International Journal of Cosmetic Science, EarlyView.
Over 8 h, using a Hyaluronic Acid Serum in combination with a Moisturizing Cream sustained skin hydration more than either product alone, while lowering TEWL and normalizing surface lipids. Volunteers also reported a more immediate and long‐lasting moisturization with the combined regimen. Created in BioRender. Maldonado Lopez, A.
Alexandra M. Maldonado López, Ivan Domicio da Silva Souza   +1 more
wiley   +1 more source