Results 131 to 140 of about 72,817 (297)

MicroRNA‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi   +11 more
wiley   +1 more source

Use of a Bacteriophage Lysin to Control Axillary Malodor

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Axillary malodor is primarily caused by bacteria, particularly Staphylococcus hominis, which metabolize apocrine secretions into volatile compounds. Traditional deodorants contain antiseptics that can disrupt the skin microbiome and cause irritation. Alternative methods of odor control are being sought but so far without success. We
Maurice A. M. van Steensel   +3 more
wiley   +1 more source

Enhanced ceramide-induced apoptosis in ceramide kinase overexpressing cells.

open access: yes, 2007
We evaluated how increased levels of ceramide kinase (CerK) would impact the growth of COS-1 fibroblasts and RBL-2H3 basophils. The low CerK activity in these cells was strongly up-regulated upon recombinant expression of CerK.
Schanzer, Andrea   +4 more
core  

A Practical Guide for Incorporating Emollients in the Treatment of Mild‐to‐Moderate Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Emollients and cleansers are essential components in managing atopic dermatitis (AD). While international evidence‐based guidelines recommend using gentle cleansers and emollients daily as a foundational therapy for AD, implementation in practice remains suboptimal.
Mette Deleuran   +12 more
wiley   +1 more source

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria

open access: yes, 2017
Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have antibacterial activity and are thought to play a more direct role in innate immunity against bacterial infections.
Schlegel, Jan   +13 more
core   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin

open access: yes, 2018
Yutaka Takagi,1 Xuanhe Ning,1 Akihiko Takahashi,1 Chiaki Ishizaki,2 Takahiro Nishizaka,1 Kazuhiro Kaizu,1 Masahiro Miyaki,1 Hotaka Yamamuro,1 Makoto Kawashima3 1Skin Care Product Research, Kao Corporation, Tokyo, Japan; 2Ebisu Skin Research Center ...
Yamamuro H   +8 more
core  

lifs-tools/ils-ceramide-ring-trial: Release 1.0

open access: yes
<h1>ILS Ceramide Ring Trial Results Evaluation Pipeline</h1> <p>This is the release 1.0 of the ILS Ceramide Ring Trial Results Evaluation Pipeline.</p> <h2>Prerequisites</h2> <p>The evaluation code requires R 4.3
Bo Burla, Nils Hoffmann
core   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider   +3 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

open access: yesMed Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu   +9 more
wiley   +1 more source

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