Results 131 to 140 of about 67,708 (303)

The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin

open access: yes, 2018
Yutaka Takagi,1 Xuanhe Ning,1 Akihiko Takahashi,1 Chiaki Ishizaki,2 Takahiro Nishizaka,1 Kazuhiro Kaizu,1 Masahiro Miyaki,1 Hotaka Yamamuro,1 Makoto Kawashima3 1Skin Care Product Research, Kao Corporation, Tokyo, Japan; 2Ebisu Skin Research Center ...
Yamamuro H   +8 more
core  

De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity

open access: yes, 2007
Previous studies could demonstrate, that the naturally occuring polyphenol resveratrol inhibits cell growth of colon carcinoma cells at least in part by inhibition of protooncogene ornithine decarboxylase (ODC). The objective of this study was to provide
Ulrich, Sandra   +4 more
core   +1 more source

Brain Serotonin Transporter Is Elevated in Obesity: Bayesian and Frequentist Meta‐Analyses

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The brain plays a critical role in controlling energy balance. Previous studies have mainly focused on dopaminergic mechanisms, whereas much less attention has been paid to serotonin during the emergence of overweight and obesity. Therefore, this study investigated the association between serotonin transporter (SERT) availability and ...
Kyoungjune Pak
wiley   +1 more source

Ceramide biosynthesis and metabolism in trophoblast syncytialization

open access: yes, 2012
Sphingolipid mediators such as ceramide are pleiotropic regulators of cellular growth, differentiation and apoptosis. We investigated the role of ceramide biosynthesis, metabolism and actions in term human cytotrophoblasts syncytialized over 7 days in ...
Singh, A.   +3 more
core   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

open access: yesThe FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump   +10 more
wiley   +1 more source

Ceramide induces apoptosis in PC12 cells

open access: yes, 1997
The novel lipid second messenger, ceramide, induced apoptosis in PC12 cells as determined morphologically by nuclear appearance and internucleosomal DNA fragmentation.
Perry J Hartfield   +5 more
core   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Sphingosine, a Product of Ceramide Hydrolysis, Influences the Formation of Ceramide Channels

open access: yes, 2006
Ceramides are known to have a regulatory function in apoptosis, including the release of cytochrome c and other proapoptotic factors from the mitochondrial intermembrane space. Ceramides can form large, stable channels in the outer mitochondrial membrane,
Fluss, Sharon   +2 more
core   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos   +3 more
wiley   +1 more source

Molecular Mechanisms of Ceramide-Mediated CD95 Clustering

open access: yes, 2001
The pattern of peptidoglycan (murein) segregation in Receptor clustering has been suggested as a crucial mechanism to initiate receptor signaling. Here we show that ceramide in sphingolipid-rich membrane rafts mediates clustering of CD95.
Schwarz, H., Grassmé , H., Gulbins, E.
core   +1 more source

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