Results 111 to 120 of about 100,829 (298)
International Journal of Biological Sciences, 2011 The activity of N-hexanoyl-D-erythro-sphingosine, a C6-ceramide against angiogenesis was tested in vitro and in vivo. The effect of ceramide in inhibiting MCF-7 cancer cells was also determined.
Rishipal R. Bansode, Mohamed Ahmedna, Kurt R. Svoboda, Jack N. Losso
doaj
Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]
, 2015 Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...
core +1 more source
Intracellular trafficking of ceramide by ceramide transfer protein
Proceedings of the Japan Academy, Series B, 2010 The transport and sorting of lipids are fundamental to membrane biogenesis. In the synthesis of sphingolipids in mammalian cells, ceramide is newly produced at the endoplasmic reticulum (ER), and transported from the ER to the trans Golgi regions, where it is converted to sphingomyelin.
openaire +3 more sources
iMetaOmics, EarlyView.Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal +4 more
wiley +1 more source
iMetaOmics, EarlyView.Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang +13 more
wiley +1 more source
MetabolitesBackground/Objectives: Ceramide, a sphingolipid metabolite, has emerged as a key player in various physiological and pathological processes. Changes in ceramide levels are associated with the occurrence and development of various diseases, highlighting ...
Xueping Shen +5 more
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Astrocytic ceramide as possible indicator of neuroinflammation
Journal of Neuroinflammation, 2019 Background Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease dementia (PDD), and frontotemporal lobar dementia (FTLD) are characterized by progressive neuronal loss but differ in their underlying pathological mechanisms ...
Nienke M. de Wit +5 more
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Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Ceramide Initiates NFκB-Mediated Caspase Activation in Neuronal Apoptosis
Neurobiology of Disease, 2000 The objective of the present study was to evaluate the role of ceramide in mediating apoptosis of dorsal root ganglion neurons induced by either nerve growth factor withdrawal or treatment with the chemotherapeutic agents suramin and cisplatin ...
Jagjit S. Gill, Anthony J. Windebank
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Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
iNew Medicine, EarlyView.Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source