Results 201 to 210 of about 99,790 (306)

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency [PDF]

, 2017
Connolly, Anne M, Cooper, Megan A, Dharnidharka, Vikas R, et al,, Willing, Marcia C   +4 more
core   +2 more sources

Reversing the effects of ceramide imbalance via anti-ceramide immunotherapy is an effective therapy for diabetic retinopathy. [PDF]

Cell Death Discov
Zhou L, Li J, Fu C, Chu WK.
europepmc   +1 more source

Linking physical stimulation to molecular responses: The role and value of exosomes in mediating the systemic effects of Chinese Tuina

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
(1) Tuina's mechanical forces activate cellular mechanosensors; (2) Induce multi‐tissue exosome release to mediate intercellular communication; (3) Exosomes systemically regulate muscle, nerve, immune and vascular functions; (4) Target gene knockout confirms exosomes’ specific mediating role.
Lifen Zhan, Ji Zhang, Yiping Chen, Suyu Chen, Xiantao Tai   +4 more
wiley   +1 more source

Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management. [PDF]

J Dermatol
Sakai T.
europepmc   +1 more source

Pre‐, Pro‐, Post‐, and Synbiotics for Skin Health: A Narrative Review of Cosmetic and Dermatological Applications

Dermatological Reviews, Volume 7, Issue 2, April 2026.
ABSTRACT Background Prebiotics, probiotics, postbiotics, and synbiotics have been increasingly investigated and incorporated into cosmetic formulations to preserve or restore skin health, function, and esthetics. Objective To review biotics applications in cosmetology, discussing their concepts, general characteristics, and potential benefits and ...
Guilherme Carvalho Tavares da Silva, Kátia de Pádua Silva, Ana Carolina Furian da Silva, Larissa Pavanello, Gabriela de Moraes Saqui, Andréa Fernandes Eloy Costa da França, Gislaine Ricci Leonardi, Karina Cogo‐Müller   +7 more
wiley   +1 more source

Oryza Ceramax in Dermatologic Care: A Multi-pathway Approach to Skin Hydration and Barrier Repair. [PDF]

Cureus
De A, Sarveswari KN, Tolat S, Hameed S, Bhat S, Jain S, Swami OC.   +6 more
europepmc   +1 more source

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan, Jianguo Sun, Makoto Kawashima, You Chan Kim, Mison Chun, Chia‐Yu Chu, Yi‐Hsin Liang, Mee Chang, Delphine Kerob, Brigitte Dreno   +9 more
wiley   +1 more source

Impact of Ceramide Acyl Chain Length on Human Skin Barrier Recovery and Hydration. [PDF]

J Cosmet Dermatol
Gwon DH, Choi HK, Lee EO, Hong SK, Park CS, Kim JW, Liu KH.   +6 more
europepmc   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source