Results 201 to 210 of about 110,293 (352)

Ceramide Formation Leads to Caspase-3 Activation during Hypoxic PC12 Cell Death [PDF]

, 1998
Shinichi Yoshimura, Yoshiko Banno, Shigeru Nakashima, Katsunobu Takenaka, Hideki Sakai, Yasuaki Nishimura, Noboru Sakai, Shigeomi Shimizu, Yutaka Eguchi, Yoshihide Tsujimoto, Yoshinori Nozawa   +10 more
openalex   +1 more source

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Sphingolipids in Gaucher disease: a systematic review. [PDF]

Orphanet J Rare Dis
Lake A, Fuller M.
europepmc   +1 more source

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang, Zhiqin Fang, Lam C. Tsoi, Johann E. Gudjonsson   +3 more
wiley   +1 more source

Acid ceramidase regulates CD8+ T-cell exhaustion via type I interferon-mediated upregulation of PD-L1. [PDF]

Front Immunol
Hu Z, Abdelrahman H, Elwy A, Kuang F, Dhiman S, Ali S, Marson M, Holnsteiner L, Hamdan TA, Friebus-Kardash J, Wiebeck E, Hansen W, Scheu S, Gulbins E, Lang PA, Lang KS, Lang J.   +16 more
europepmc   +1 more source

Interferon-γ Decreases Cell Surface Expression of Galactosyl Ceramide, the Receptor for HIV-1 GP120 on Human Colonic Epithelial Cells

, 1994
Nouara Yahi, Steven L. Spitalnik, Kelly Stefano, Philippe de Micco, Francisco González‐Scarano, Jacques Fantini   +5 more
openalex   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

Prevention of chemotherapy-induced apoptotic follicular death in human ovary by ceramide-induced death pathway inhibitors [PDF]

, 2010
Reza Soleimani, Elke Heytens, Kutluk Oktay   +2 more
openalex   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD. [PDF]

EBioMedicine
Mandala A, Undi RB, Janssen RC, Sugino KY, Zhao W, Nelson BN, Teague AM, Patil NY, Zemsky Berry K, Varshney R, Bergman BC, Rudolph MC, Joshi AD, Rajala RVS, Jonscher KR, Friedman JE.   +15 more
europepmc   +1 more source