Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells. [PDF]
Mechleb K +13 more
europepmc +1 more source
On why cancer cells require a great amount of glucose
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu +6 more
wiley +1 more source
Skin Barrier Dysfunction in Contact and Atopic Dermatitis: A Comparative Review. [PDF]
Maeng J, Jeong S, Kim H.
europepmc +1 more source
Sphingosine‐1‐Phosphate Promotes FOS Activation in Osteosarcoma Under Tumor Acidosis
ABSTRACT Aim The tumor microenvironment in solid tumors is characterized by extracellular acidosis, which promotes cancer aggressiveness. In osteosarcoma, the most common primary bone cancer, a highly acidic tumor microenvironment is associated with metastasis and poor prognosis, partly due to metabolic rewiring, including changes in lipid pathways ...
Nicolò Bozzini +9 more
wiley +1 more source
Ceramide-Infused Skin Barrier for Use Following Ostomy Surgery: A Narrative Review of Available Data. [PDF]
Berger A +4 more
europepmc +1 more source
Linear ion-trap MSn with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis [PDF]
Hsu, Fong-Fu +3 more
core +2 more sources
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni +7 more
wiley +1 more source
Sphingolipids in Emotional Well-Being. [PDF]
Kalinichenko LS +4 more
europepmc +1 more source
CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish [PDF]
Biswas, Lincoln +17 more
core +1 more source
Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source

