Results 201 to 210 of about 67,929 (292)

Influenza A Virus Infection Induces Preferential Increases in Long-Chain Ceramides. [PDF]

Viruses
McKenna S, Jung KI, Sumner B, Wolf JJ, Sumner LW, Hahm B.   +5 more
europepmc   +1 more source

Chemogenetic Activation of G12 Signaling Thickens the Epidermis With Enhanced Barrier Function

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
In this study, we investigated the role of G12 signaling in the epidermis using a keratinocyte‐specific chemogenetic approach. Activation of G12 signaling promoted keratinocyte differentiation and enhanced epidermal barrier function by upregulating filaggrin, claudin‐1, and ceramide.
Nozomi Kamakura, Natsumi Hirai, Kaito Arai, Yaxin Du, Toshiaki Kogame, Yusuke Ohno, Akio Kihara, Kenji Kabashima, Asuka Inoue   +8 more
wiley   +1 more source

Ceramide production at the plasma membrane [PDF]

, 2009
M. Aureli, V.L. Chigorno, A.P. Masilamani, A.E.G. Prinetti, S. Sonnino, N. Loberto, G. Illuzzi   +6 more
core  

Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits? [PDF]

J Am Soc Nephrol
Saum KL, Pennathur S.
europepmc   +1 more source

Muscle Mitochondrial Oxidative Capacity and Cognitive Decline Over up to a Decade: Sex Differences

Aging Cell, Volume 25, Issue 8, August 2026.
Skeletal muscle mitochondrial oxidative capacity is linked to cognition and predicts cognitive decline primarily in men. Underlying mechanisms appear to differ by sex, likely through a metabolic‐drive pathway in men and a hematologic‐inflammatory pathway in women.
Qu Tian, Anjay Ambegaonkar, Luigi Ferrucci   +2 more
wiley   +1 more source

Altered Sphingolipid Metabolism is Associated with Osimertinib Resistance in Nonsmall-Cell Lung Cancer. [PDF]

J Proteome Res
Babuta J, Gruevska A, Wickremesinghe C, Montoya A, Roumelioti G, Shliaha P, Balcells C, McKinney F, Bray C, Athersuch T, Martin M, Keun H, Hall Z.   +12 more
europepmc   +1 more source

Jiuwei Xiaozhi Decoction Alleviates High‐Fat Diet‐Induced MASLD by Suppressing Hepatic SREBP2‐Driven Cholesterogenesis and Restoring PPARα‐Mediated Fatty Acid Oxidation

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Studies have found that Jiuwei Xiaozhi Decoction can improve high‐fat diet‐induced fatty liver disease, mainly by regulating the SREBP2 and PPARα pathways to balance hepatic lipid metabolism while reducing inflammatory responses. ABSTRACT Jiuwei Xiaozhi Decoction (JWXZ) is a nine‐herb traditional Chinese medicine formula clinically used for hepatic ...
Youcheng Ma, Xinrui Gao, Ji Wang, Lingru Li, Zhen Huang, Fangli Li   +5 more
wiley   +1 more source

IL-4/IL-13-Driven Dysregulation of Epidermal Lipid Metabolism in Atopic Dermatitis: An Immunometabolic Link Between Type 2 Inflammation and Barrier Dysfunction. [PDF]

Cells
Andrzejczak K, Sternak A, Witkowski W, Flak A, Maj J, Ponikowska M.   +5 more
europepmc   +1 more source

Absorption and Effects of Patch Test Preparations of Hydroperoxides of Limonene and Hydroperoxides of Linalool in Human Ex Vivo Skin

Contact Dermatitis, Volume 95, Issue 2, Page 159-168, August 2026.
This study mimics clinical patch testing for the diagnosis of allergic contact dermatitis, by application of patch test preparations of fragrance terpenes to ex vivo human skin samples. The study investigates the penetration of linalool hydroperoxide and limonene hydroperoxide in skin, alongside an analysis of the lipid‐modifying effects of the patch ...
Aoife Clancy, Lina Hagvall, Per Malmberg, Niamh M. O'Boyle   +3 more
wiley   +1 more source

Reconstruction of Molecular Interaction Patterns from Endolysosomes in Ceramide-Depleted Cells. [PDF]

Nano Lett
Feng Y, Gärber F, Spedalieri C, Werner S, Pratsch C, Arenz C, Seifert S, Kneipp J.   +7 more
europepmc   +1 more source