Results 211 to 220 of about 160,293 (302)

Bilateral ictal eye closure in focal epileptic seizures: SEEG retrospective observational assessment from a tertiary epilepsy center

open access: yesEpileptic Disorders, EarlyView.
Abstract Ictal eye closure is commonly associated with functional seizures but may also occur in epileptic seizures. We retrospectively reviewed 113 consecutive stereo‐EEG (SEEG) recordings from adults with drug‐resistant focal epilepsy (2015–2024) to identify prolonged bilateral eye closure during seizures.
Paola Vassallo   +10 more
wiley   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing   +4 more
wiley   +1 more source

Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex. [PDF]

open access: yesNat Commun
Han X   +20 more
europepmc   +1 more source

Arterial spin labeling performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to test whether arterial spin labeling (ASL) performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET), the mainstay functional imaging technique, in pediatric lesional epilepsy, while avoiding radiotracer exposure and additional sedation.
Antonio Giulio Gennari   +7 more
wiley   +1 more source

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

open access: yesEpilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu   +11 more
wiley   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh   +3 more
wiley   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil   +4 more
wiley   +1 more source

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