Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases [PDF]
Scientific Reports, 2022 The establishment of robust human brain organoids to model cerebellar diseases is essential to study new therapeutic strategies for cerebellum-associated disorders.
João Brás +9 more
doaj +2 more sources
Consensus Paper: Radiological Biomarkers of Cerebellar Diseases [PDF]
Cerebellum, 2015 Hereditary and sporadic cerebellar ataxias represent a vast and still growing group of diseases whose diagnosis and differentiation cannot only rely on clinical evaluation.
A D’Abreu +176 more
core +2 more sources
Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo. [PDF]
PLoS ONE, 2009 The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits.
Cristina Granziera +6 more
doaj +3 more sources
Cerebellar Dysfunction in Multiple Sclerosis
Frontiers in Neurology, 2017 Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat ...
Alastair Wilkins
doaj +3 more sources
Automated cerebellar lobule segmentation with application to cerebellar structural analysis in cerebellar disease [PDF]
NeuroImage, 2016 The cerebellum plays an important role in both motor control and cognitive function. Cerebellar function is topographically organized and diseases that affect specific parts of the cerebellum are associated with specific patterns of symptoms. Accordingly, delineation and quantification of cerebellar sub-regions from magnetic resonance images are ...
Zhen Yang, Chuyang Ye, John A Bogovic
exaly +4 more sources
Clinical Characteristics and Effects of Steroid Therapy in Children with Acute Cerebellar Ataxia [PDF]
Annals of Child Neurology, 2021 Purpose Acute cerebellar ataxia (ACA) is characterized by unsteady gait and instability of the trunk, and is caused by secondary autoimmune responses to infection or vaccination in healthy children.
Joo Young Lee +4 more
doaj +1 more source
Anesthetic considerations of Joubert syndrome in patients with mitochondrial disease - A case report - [PDF]
Anesthesia and Pain Medicine, 2021 Background Joubert syndrome and mitochondrial disease are rare congenital diseases in which a wide range of symptoms affects multiple organs. Patients with these diseases present characteristic symptoms related to the musculoskeletal, respiratory, and ...
Jeong Yeon Kim +5 more
doaj +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective Summarize the clinical characteristics and treatment plan of 2 cases of abnormal anastomosis at the origin of the posterior inferior cerebellar artery (PICA) complicated with aneurysm.
YIN Hong⁃wei +5 more
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Cerebellar cognitive affective syndrome due to cerebellar atrophy: case report
Geriatrics, Gerontology and Aging, 2022 Cerebellar atrophy is a rare and challenging disease with few descriptions in the medical literature. Motor impairment is mild, but behavioral and linguistic alterations stand out, in what is known as the cerebellar cognitive affective syndrome secondary
Einstein Francisco Camargos +3 more
doaj +1 more source
Neuroimaging of Pediatric Cerebellum in Inherited Neurodegenerative Diseases
Applied Sciences, 2021 In the study of cerebellar degenerative diseases, morphologic imaging (computed tomography, CT and magnetic resonance imaging, MRI) is the most common examination.
Luisa Chiapparini, Marco Moscatelli
doaj +1 more source