Results 61 to 70 of about 104,697 (299)

Task Force Paper On Cerebellar Transplantation: Are We Ready to Treat Cerebellar Disorders with Cell Therapy? [PDF]

, 2019
Restoration of damaged central nervous system structures, functional recovery, and prevention of neuronal loss during neurodegenerative diseases are major objectives in cerebellar research. The highly organized anatomical structure of the cerebellum with
Buffo, Annalisa, Vozeh, Frantisek, Hirai, Hirokazu, Mitoma, Hiroshi, Sherrard, Rachel, Manto, Mario, Magrassi, Lorenzo, Cendelin, Jan   +7 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Cerebellar degeneration in primary Sjögren syndrome: a case report

Journal of Medical Case Reports, 2021
Background Cerebellar degeneration is a rare and severe presentation of primary Sjögren syndrome. There are few case reports of cerebellar degeneration associated with different autoimmune diseases, especially with systemic lupus erythematosus and neuro ...
Seow Lin Chuah, Ahmad Tirmizi Jobli, Sharifah Aishah Wan, Cheng Lay Teh   +3 more
doaj   +1 more source

Deafness and vestibulopathy in cerebellar diseases: a practical approach [PDF]

, 2020
Cerebellar ataxias are a clinically heterogeneous group of neurological disorders. Besides the cerebellum, several forms of hereditary ataxias or non-genetic ataxias also affect other areas of the brain. Some forms of cerebellar ataxias may have cochlear
Barsottini, Orlando G., Franca, Marcondes Cavalcante Jr., Albernaz, Pedro Mangabeira, Pedroso, Jose Luiz, Martins, Carlos Roberto Jr.   +4 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Differential diagnosis of hot cross bun sign

Archives of Medicine and Health Sciences, 2019
Multiple system atrophy (MSA) is a term that represents a group of neurodegenerative diseases characterized by different levels of autonomic, cerebellar, parkinsonism, and pyramidal features. Hereinafter, we report a case of an elderly male who presented
Jamir Pitton Rissardo, Ana Letícia Fornari Caprara   +1 more
doaj   +1 more source

The Relationships Between The Superior Cerebellar Artery and Trochlear Nerve [PDF]

, 2009
Trochlear nerve palsy has been based on head trauma, various inflammatory and infectious disorders, vascular diseases and neoplasms. In many cases cause of the nerve palsy unclear.
Eray Tüccar, S. Tuna Karahan, Ali Fırat Esmer, Tülin Şen   +3 more
core  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum

Scientific Reports, 2017
The directed differentiation of patient-derived induced pluripotent stem cells into cell-type specific neurons has inspired the development of therapeutic discovery for neurodegenerative diseases.
Gustavo A. Higuera, Grazia Iaffaldano, Meiwand Bedar, Guy Shpak, Robin Broersen, Shashini T. Munshi, Catherine Dupont, Joost Gribnau, Femke M. S. de Vrij, Steven A. Kushner, Chris I. De Zeeuw   +10 more
doaj   +1 more source

Cellular Commitment in the Developing Cerebellum

Frontiers in Cellular Neuroscience, 2015
The mammalian cerebellum is located in the posterior cranial fossa and is critical for motor coordination and non-motor functions including cognitive and emotional processes. The anatomical structure of cerebellum is distinct with a three-layered cortex.
Hassan eMarzban, Marc R. Del Bigio, Marc R. Del Bigio, Javad eAlizadeh, Saeid eGhavami, Robby M. Zachariah, Robby M. Zachariah, Mojgan eRastegar, Mojgan eRastegar   +8 more
doaj   +1 more source