RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro +4 more
wiley +1 more source
Radiological Spectrum of Leptomeningeal Medulloblastoma: A Case-Based Literature Review With an Additional Case Report. [PDF]
Cigdem Karatayli E +5 more
europepmc +1 more source
Accelerating MRI With Longitudinally‐Informed Latent Posterior Sampling
ABSTRACT Purpose To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex relationship between scan sessions, potentially involving substantial anatomical or pathological changes, and ...
Yonatan Urman +4 more
wiley +1 more source
Rapidly Progressive Cerebellar Syndrome Associated With Anti-Yo Antibodies Following Complete Response to Advanced Ovarian Carcinoma Treated With Olaparib: A Case Report. [PDF]
Carvalho S, Lopes AC, Lopes AR.
europepmc +1 more source
ABSTRACT Purpose To apply the Magnetization Transfer Indirect Spin Labeling (MISL) MRI technique for quantifying tissue‐CSF water exchange in the human brain, and to investigate its utility in (1) evaluating tissue‐CSF water exchange within perivascular spaces (PVS), and (2) characterizing altered water exchange dynamics in pathologic conditions ...
Yihan Wu +8 more
wiley +1 more source
Cerebellar pilocytic astrocytoma in a patient with autism spectrum disorder and psychotic symptoms: a case report. [PDF]
Itami K +5 more
europepmc +1 more source
Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved +4 more
wiley +1 more source
Risk factors associated with cerebellar mutism syndrome and late postoperative hydrocephalus following pediatric posterior fossa medulloblastoma surgery. [PDF]
Du J +5 more
europepmc +1 more source

