Results 91 to 100 of about 578,102 (305)

MRI Atlas of the Human Cerebellar Nuclei

NeuroImage, 2002
The differential role of the cerebellar cortex and nuclei has rarely been addressed in human lesion and functional brain imaging studies. One important reason is the difficulty of defining the localization of the cerebellar nuclei and extent of possible lesions based on CT or MR scans.
Dimitrova, A., Weber, Johannes, Redies, C., Kindsvater, Kerstin, Maschke, Matthias, Kolb, Florian P., Forsting, Michael, Diener, Hans-Christoph, Timmann, Dagmar   +8 more
openaire   +3 more sources

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics

Frontiers in Neural Circuits
The cerebellar output can trigger whisker movement through indirect projections that pass via several brainstem pre-motor nuclei before reaching the facial nucleus, which directly controls whisker movements in rodents.
Staf Bauer, Peipei Zhai, Nathalie van Wingerden, Hehe Zhao, Vincenzo Romano   +4 more
doaj   +1 more source

Sensorimotor processing for balance in spinocerebellar ataxia type 6. [PDF]

, 2015
We investigated whether balance impairments caused by cerebellar disease are associated with specific sensorimotor processing deficits that generalize across all sensory modalities.
Bunn, LM, Day, BL, Giunti, P, Marsden, JF, Voyce, DC   +4 more
core   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation

eLife, 2020
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear.
Amanda M Brown, Joshua J White, Meike E van der Heijden, Joy Zhou, Tao Lin, Roy V Sillitoe   +5 more
doaj   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

A double-label study of efferent projections from the Edinger-Westphal nucleus in goldfish and kelp bass [PDF]

, 1988
The Edinger-Westphal nucleus in goldfish was identified by retrograde labeling from the ciliary ganglion. In the same animals a few neurons near this nucleus (perinuclear Edinger-Westphal neurons) were labeled by a different retrograde tracer injected ...
Akert, Burde, Carlton, Castiglioni, Clarke, Innis, John C. Wathey, Johnson, Kuypers, Leong, Loewy, Maciewicz, Maciewicz, Mario F. Wullimann, Mesulam, Scherer, Schmued, Sekiya, Sivak, Springer, Sugimoto, Toyoshima, Wathey   +22 more
core   +1 more source

Strength and timing of motor responses mediated by rebound firing in the cerebellar nuclei after Purkinje cell activation

Front. Neural Circuits, 2013
The cerebellum refines the accuracy and timing of motor performance. How it encodes information to perform these functions is a major topic of interest.
L. Witter, Cathrin B. Canto, T. Hoogland, J. R. De Gruijl, C. D. De Zeeuw   +4 more
semanticscholar   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source