Results 121 to 130 of about 368,839 (349)
Advanced Science, EarlyView.This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang +12 more
wiley +1 more source
Jurnal Sain Veteriner, 2014 Long tailed macaque was one of animal models in biomedical research because it has many similarities with humans, both anatomical and physiological properties.
Tri Wahyu Pangestiningsih +2 more
doaj +1 more source
Activation of Ras-ERK pathway by Fgf8 and its downregulation by Sprouty2 for the isthmus organizing activity [PDF]
, 2008 In the previous studies, we showed that strong Fgf8 signaling activates the Ras-ERK pathway to induce cerebellum. Here, we show importance of negative regulation of this pathway.
Asuka Suzuki-Hirano +2 more
core +1 more source
Buckling without bending: a new paradigm in morphogenesis
, 2018 A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the oscillations ...
Engstrom, T. A. +4 more
core +1 more source
Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
The development of the cerebellum in the frog (Hyla regilla) in relation to the vestibular and lateral‐line systems [PDF]
, 1925 O. Larsell
openalex +1 more source
Advanced Science, EarlyView.Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu +5 more
wiley +1 more source
Papel do cerebelo nas funções cognitivas e comportamentais: bases científicas e modelos de estudo.
Acta Médica Portuguesa, 2006 Although classically considered to be involved only in motor coordination, the cerebellum has more recently been implicated also in cognitive control.
Paulo Bugalho +2 more
doaj +1 more source
Advanced Science, EarlyView.This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu +17 more
wiley +1 more source