Results 121 to 130 of about 354,424 (374)

Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar, Arnold M. Evia, Mahir Tazwar, Sue E. Leurgans, David A. Bennett, Julie A. Schneider, Konstantinos Arfanakis   +6 more
wiley   +1 more source

Inositol 1,4,5-triphosphate receptor is selectively expressed in cerebellum but not cerebellum-like structures of the elasmobranch fish, Leucoraja erinacea

Heliyon, 2019
The Inositol 1,4,5-trisphosphate receptor type 1 protein (Ip3r1) performs an essential role for the induction of cerebellar long-term depression. Here, I describe the use of RT-PCR, qPCR, western blotting and immunohistochemistry to assay Ip3r1 gene ...
Christos Michael Suriano
doaj  

The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

Frontiers in Neuroscience, 2015
The cerebellum has been repeatedly implicated in gene expression, rodent model and post-mortem studies of autism spectrum disorder (ASD). How cellular and molecular anomalies of the cerebellum relate to clinical manifestations of ASD remains unclear ...
Matthew W Mosconi, Matthew W Mosconi, Zheng eWang, Lauren M Schmitt, Peter eTsai, John A Sweeney   +5 more
doaj   +1 more source

Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors. [PDF]

, 2016
The role of the cerebellum in motivation and addictive behaviors is less understood than that in control and coordination of movements. High running can be a self-rewarding behavior exhibiting addictive properties.
Caetano-Anollés, Kelsey, Garland, Theodore, Hernandez, Alvaro G, Perez, Sam D, Rhodes, Justin S, Rodriguez-Zas, Sandra L, Southey, Bruce R   +6 more
core   +2 more sources

Programming the cerebellum [PDF]

Behavioral and Brain Sciences, 1996
ISSN:0140 ...
openaire   +3 more sources

Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić, Sanda Pavelin, Nikolina Pleić, Joško Šoda, Krešimir Dolić, Anita Markotić, Ana Ćurković Katić, Angela Mastelić, Nikolina Režić Mužinić, Jasna Duranović, Zlatko Kljajić, Ivona Stipica Safić, Zoran Đogaš, Maja Rogić Vidaković   +13 more
wiley   +1 more source

Different coding characteristics between flight and freezing in dorsal periaqueductal gray of mice during exposure to innate threats

Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 491-501, December 2022., 2022
Flight and freezing are two vital defensive behaviors in the process of avoiding natural enemies in mice. We investigated the neural activity in dPAG nuclei of mice under two defensive behaviors, and found different coding features between flight and freezing behaviors. Abstract Background Flight and freezing are two vital defensive behaviors that mice
Denghui Liu, Shouhao Li, Liqing Ren, Xinyu Liu, Xiaoyuan Li, Zhenlong Wang   +5 more
wiley   +1 more source

Small variation in dynamic functional connectivity in cerebellar networks [PDF]

arXiv, 2020
Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional connectivity (DFC).
arxiv  

mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors [PDF]

, 2018
In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of synaptic innervation during postnatal development.
Atsu Aiba, Cristina Zappulla, Ferdinando Nicoletti, Francesca Liberatore, Giada Mascio, Giorgio Carmignoto, Giuseppe Battaglia, Harumi Nakao, Marta Motolese, Masahiko Watanabe, Micaela Zonta, Michele Madonna, Milena Cannella, Pamela Scarselli, Roberto Gradini, Serena Notartomaso, Valeria Bruno   +16 more
core   +2 more sources

CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh, Yoonhyuk Jang, Soo Jean Shin, Soo Hyun Ahn, Su Yee Mon, Yoon Hee Shin, Kon Chu, Sang Kun Lee, Soon‐Tae Lee   +8 more
wiley   +1 more source