Results 191 to 200 of about 368,839 (349)

THE MIDDLE PEDUNCLE OF THE CEREBELLUM [PDF]

, 1885
NULL AUTHOR_ID
openalex   +1 more source

A Drosophila model of prion disease and its metabolic changes in the brain

Animal Models and Experimental Medicine, EarlyView.
We developed a Drosophila model for prion disease, and flies were capable of expressing the hamster prion protein (HaPrP) under the control of the GAL4/UAS system. The model exhibited some characteristics of the disease in mammals and displayed alterations in protein, sphingolipid, and carbohydrate metabolism. Preliminary applications have demonstrated
Dongdong Wang, Zhixin Sun, Pei Wen, Mengyang Zhao, Yuheng He, Fengting Gou, Jingjing Wang, Qing Fan, Xueyuan Li, Tianying Ma, Xiaoyu Wang, Wen Li, Sen Chen, Deming Zhao, Lifeng Yang   +14 more
wiley   +1 more source

Arginine Metabolism and Adenosine Receptor Signals in the Cerebellum Contribute to Nicotine Withdrawal-Induced Anxiety/Depression-Like Behaviours. [PDF]

Addict Biol
Zhang W, Tian Y, Yang X, He B, Zhang H, Zhang Q, Mei Y.   +6 more
europepmc   +1 more source

A BENIGN "TUMOUR" OF THE CEREBELLUM: REPORT ON TWO CASES OF DIFFUSE HYPERTROPHY OF THE CEREBELLAR CORTEX WITH A REVIEW OF NINE PREVIOUSLY REPORTED CASES

, 1955
D. R. Oppenheimer
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Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage

Animal Models and Experimental Medicine, EarlyView.
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu, Aoqi Liu, Yijia He, Fei Li, Zhouyang Jiang, Peiwen Guo, Zhi Chen, Yujie Chen, Hua Feng   +8 more
wiley   +1 more source

Caffeine-augmented exercise as a pretreatment for locomotor and balance impairments induced by REM sleep deprivation in rats. [PDF]

Sci Rep
Karami E, Sarkaki A, Farbood Y, Moradi Vastegani S.   +3 more
europepmc   +1 more source

CHRONIC DIFFUSE DISEASE OF THE CEREBELLUM [PDF]

, 1921
B. Brouwer
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Comparative analysis of two newly established Cre rat lines, NeuN‐Cre and Thy1‐Cre, for neurological research

Animal Models and Experimental Medicine, EarlyView.
We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li, Chenyang Liu, Gefan Wan, Lei Zhang, Rui Fan, Xu Zhang, Yuanlong Su, Jiayue He, Ning Liu, Feifei Guan, Wei Dong, Shan Gao, Weining Kong, Xiaolong Qi, Xiaolin Zhang, Yuanwu Ma   +15 more
wiley   +1 more source

Establishment and molecular profiling of a PDX model of a metachronous brain tumor in a patient with constitutional mismatch repair deficiency with biallelic MSH6 variant

Animal Models and Experimental Medicine, EarlyView.
A 6½‐year‐old girl was diagnosed with a medulloblastoma, SHH activated, subtype 3 and TP53 mutant (somatic). After surgery and chemotherapy, she was monitored with quarterly magnetic resonance imaging (MRI) scans and remained free of disease for almost 4 years.
Daniel Antunes Moreno, Bruna Minniti Mançano, Mirella Baroni, Eric Allison Philot, Felipe Antonio de Oliveira Garcia, Murilo Bonatelli, Flávia Escremim de Paula, Iara Viana Vidigal Santana, Gustavo Ramos Teixeira, Mauricio Yamanari, Luciane Sussuchi da Silva, André Escremim de Paula, Augusto Perazzolo Antoniazzi, Adrian Willig, Xiaobin Xing, Zhenyu Xu, Lucas Lourenço, Carlos Almeida Junior, Silvia Aparecida Teixeira, Rui Manuel Reis   +19 more
wiley   +1 more source

A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype. [PDF]

Commun Biol
Greene S, Talbert ML, Frost FG, Zerfas PM, Springer D, Noguchi A, Morimoto M, Maynard D, Garrett L, Elliot G, Traver M, Yarnell D, Leoyklang P, Burke JD, Nicoli ER, Gahl WA, Introne WJ, Malicdan MCV.   +17 more
europepmc   +1 more source