Results 61 to 70 of about 461,280 (380)

The cerebellum and dyslexia

Cortex, 2011
Developmental dyslexia is defined as deficient literacyacquisition despite adequate intellectual ability and sufficienteducational provision (World Federation of Neurology;American Psychological Association, 2000). The dominanttheory of dyslexia proposes that a phonological processingdeficit – difficulty associating letters with the appropriatesounds ...
Stoodley, C, Stein, J
openaire   +4 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]

, 2017
Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali, An, Archambault, Brian P. Daniels, Brien, Cramer, Daniels, Douglas M. Durrant, Furr, Furr, Getts, Harsha Jujjavarapu, Hart, Helen M. Lazear, James P. White, Jessica L. Williams, Michael Gale, Michael S. Diamond, Morga, Pfefferkorn, Richard R. Green, Robyn S. Klein, Rothhammer, Wang   +23 more
core   +3 more sources

Morphological development of the dorsal hindbrain in an elasmobranch fish (Leucoraja erinacea)

Zoological Letters, 2018
The developmental anatomy of the dorsal hindbrain in an elasmobranch fish, Leucoraja erinacea, is described. We focus on the cerebellum, which is a synapomorphy for gnathostomes. Cerebellar development in L.
Christos Michael Suriano, David Bodznick
doaj   +1 more source

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source

Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum [PDF]

, 2019
Cerebellar Purkinje cell (PC) loss is a consistent pathological finding in autism. However, neural mechanisms of PC-dysfunction in autism remain poorly characterized.
Chiu, Shu-Ling, Gil Infante, Ana, Huganir, Richard L, Mejías Estévez, Rebeca María, Rose, Rebecca, Wang, Tao, Zhao, Yifan   +6 more
core   +1 more source

Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi, Samantha N. Roman, Mohammad S. Sadaghiani, Lilja B. Solnes, Scott D. Newsome   +4 more
wiley   +1 more source

Adaptive Neural Models of Queuing and Timing in Fluent Action [PDF]

, 2003
Temporal structure in skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefrontal cortex appear to be queued for performance by a cyclic competitive ...
Bullock, Daniel
core   +1 more source

Cerebellar Morphometry and Cognition in the Context of Chronic Alcohol Consumption and Cigarette Smoking. [PDF]

, 2020
BackgroundCerebellar atrophy (especially involving the superior-anterior cerebellar vermis) is among the most salient and clinically significant effects of chronic hazardous alcohol consumption on brain structure.
Cootes T, Fregly AR, Harper CG, Sullivan EV, Victor M, Wang X   +5 more
core   +1 more source

Functional and volumetric cortico-cerebellar alterations in congenital blind children associated with language processing

Journal of Magnetic Resonance Open, 2022
Introduction: Visual deprivation affects learning and cognition, and maybe associated with structural and functional changes in the cerebral and cerebellar areas.
A Ankeeta, S Senthil Kumaran, Rohit Saxena   +2 more
doaj   +1 more source