Results 51 to 60 of about 258,614 (316)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

The evolution of the primate cerebellum [PDF]

, 2001
Investigations into the evolution of the primate brain have consistently focussed on the neocortex as the principal area of change. New evidence is presented here to show that the cerebellum has also shown significant expansion over primate brain ...
Whiting, Bryony Anneke
core  

Gray matter density loss in essential tremor: a lobule by lobule analysis of the cerebellum [PDF]

, 2017
BACKGROUND: The pathophysiological basis for essential tremor (ET) remains unclear, although evidence increasingly links it to a disordered and perhaps degenerative cerebellum. Prior imaging studies have treated the cerebellum en bloc.
Dyke, Jonathan P., Cameron, Eric, Elan D. Louis, Dydak, Ulrike, Nora Hernandez, Ulrike Dydak, Hernandez, Nora, Jonathan P. Dyke, Louis, Elan D., Eric Cameron   +9 more
core   +1 more source

The Significance of the Granular Layer of the Cerebellum, by Professor Heinrich Obersteiner (English Translation)

, 2021
The paper is an English translation of Heinrich Obersteiner's lecture on the significance of the granular layer of the cerebellum, rendered from the original German text that was published under the title Über die Bedeutung der Körnerschichte des ...
Triarhou, Lazaros
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Consensus paper: cerebellum and social cognition [PDF]

, 2020
The traditional view on the cerebellum is that it controls motor behavior. Although recent work has revealed that the cerebellum supports also non-motor functions such as cognition and affect, only during the last 5 years it has become evident that the ...
Qianying Ma, Sokolov, A.A., Heleven, Elien, Guell X, Michelutti M., Manto M., Laura C. Rice, Arseny A. Sokolov, Heleven E., Stoodley C. J., Michelutti, M., Cattaneo, Z., Gabrieli J. D. E., Manto M, Van Overwalle F., Pu, Min, Vandervert, Larry, Pu M, Stoodley CJ, Schmahmann JD, Sokolov, Arseny A., Giusy Olivito, Clausi S, Ferrari, C., Leggio, Maria, Lupo, M., Vandervert L., Ferrari, Chiara, Larry Vandervert, Olivito, G., Cattaneo Z, Stoodley, Catherine J., Gabrieli, JDE, Heleven E, Vandervert, L., Ferrari C, Silvia Clausi, Manto, M., Gabrieli, John D. E., Lupo M., Ma, Qianying, Siciliano L., Van Overwalle, F., Rice LC, Cattaneo, Zaira, Siciliano, Libera, Catherine J. Stoodley, Clausi, S., Gabrieli, John D E, Ma Q., Rice L. C., Lupo, Michela, Min Pu, Stoodley, Catherine J, Jeremy D. Schmahmann, Schmahmann J. D., Frank Van Overwalle, Cattaneo Z., Pu, M., Van Overwalle F, Guell X., Chiara Ferrari, Heleven, E., Xavier Guell, Michela Lupo, Rice, Laura C., Michelutti, Marco, Olivito, Giusy, Guell, Xavier, Siciliano L, Leggio M., Rice, L.C., Guell, X., van Dun, K., Schmahmann, Jeremy D, Michelutti M, Schmahmann, J.D., Van Overwalle, Frank, Mario Manto, Clausi S., van Dun, Kim, Lupo M, Schmahmann, Jeremy D., Ma Q, Pu M., Leggio M, Olivito G, Marco Michelutti, Kim van Dun, Zaira Cattaneo, Elien Heleven, Sokolov A. A., Maria Leggio, Clausi, Silvia, van Dun K, Vandervert L, Gabrieli JDE, Libera Siciliano, Stoodley, C.J., Sokolov AA, Olivito G., Rice, Laura C, Ferrari C., Leggio, M., Ma, Q., John D. E. Gabrieli, Manto, Mario, Siciliano, L., van Dun K.   +108 more
core   +1 more source

Morphological development of the dorsal hindbrain in an elasmobranch fish (Leucoraja erinacea)

Zoological Letters, 2018
The developmental anatomy of the dorsal hindbrain in an elasmobranch fish, Leucoraja erinacea, is described. We focus on the cerebellum, which is a synapomorphy for gnathostomes. Cerebellar development in L.
Christos Michael Suriano, David Bodznick
doaj   +1 more source

Functional and volumetric cortico-cerebellar alterations in congenital blind children associated with language processing

Journal of Magnetic Resonance Open, 2022
Introduction: Visual deprivation affects learning and cognition, and maybe associated with structural and functional changes in the cerebral and cerebellar areas.
A Ankeeta, S Senthil Kumaran, Rohit Saxena   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Cerebellum to motor cortex paired associative stimulation induces bidirectional STDP-like plasticity in human motor cortex

, 2012
The cerebellum is crucially important for motor control and adaptation. Recent non-invasive brain stimulation studies have indicated the possibility to alter the excitability of the cerebellum and its projections to the contralateral motor cortex, with ...
Tsai, Chon-Haw, Chon-Haw Tsai, Ming-Kuei Lu, Lu, Ming-Kuei, Ulf Ziemann, Ziemann, Ulf   +5 more
core   +1 more source