Results 31 to 40 of about 218,927 (266)

Cerebellar deep brain stimulation rescues Purkinje cell mitochondrial density in a genetic mouse model of cerebellar ataxia

open access: yesBrain Research Bulletin
Deep brain stimulation (DBS) improves motor function in a growing list of movement diseases including Parkinson’s disease, dystonia, and tremor. There is evidence that DBS may also be effective in ataxia.
Lauren N. Miterko-Myers   +4 more
doaj   +1 more source

TUMOR OF THE CEREBELLUM [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1889
n ...
openaire   +2 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Effect of Tramadol on offspring's of Pregnant female Albino Rats' Cerebellum

open access: yesMinia Journal of Medical Research, 2023
Background: :Cerebellum is a vital component in the human brain as it plays a role in motor movement regulation and balance control. The cerebellum coordinates gait and maintains posture, controls muscle tone and voluntary muscle activity .cerebellum is
shimaa abdelbaset   +4 more
doaj   +1 more source

TERATOMA OF CEREBELLUM [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1921
n ...
openaire   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver   +25 more
wiley   +1 more source

Cerebellar motor and non-motor contributions to dystonia pathophysiology and treatment

open access: yesDystonia
Dystonia is a complex neurological disorder characterized by sustained or intermittent abnormal movements and/or postures. However, dystonia’s non-motor symptoms, particularly the sleep disturbances, are critical yet underexplored concerns that affect ...
Linda H. Kim   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural atrophy and functional dysconnectivity patterns in the cerebellum relate to cerebral networks in svMCI

open access: yesFrontiers in Neuroscience, 2023
Subcortical vascular mild cognitive impairment (svMCI) is associated with structural and functional changes in the cerebral cortex affecting major brain networks.
Alaka Acharya   +5 more
doaj   +1 more source

The Sleeping Cerebellum [PDF]

open access: yesTrends in Neurosciences, 2017
We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the ...
Cathrin B. Canto   +4 more
openaire   +2 more sources

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