Results 61 to 70 of about 276,134 (314)

The cerebellum in children with spina bifida and Chiari II malformation: Quantitative volumetrics by region

open access: yes, 2010
Few volumetric MRI studies of the entire cerebellum have been published; even less quantitative information is available in patients with hindbrain malformations, including the Chiari II malformation which is ubiquitous in patients with spina bifida ...
Juranek, Jenifer   +4 more
core   +1 more source

Consensus Paper: Experimental Neurostimulation of the Cerebellum [PDF]

open access: yes, 2019
The cerebellum is best known for its role in controlling motor behaviors. However, recent work supports the view that it also influences non-motor behaviors.
Louis, Elan D   +117 more
core   +3 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Cerebellar Circuits for Classical Fear Conditioning

open access: yesFrontiers in Cellular Neuroscience, 2022
Accumulating evidence indicates that the cerebellum is critically involved in modulating non-motor behaviors, including cognition and emotional processing.
Kyoung-Doo Hwang   +9 more
doaj   +1 more source

Consensus paper: cerebellum and social cognition [PDF]

open access: yes, 2020
The traditional view on the cerebellum is that it controls motor behavior. Although recent work has revealed that the cerebellum supports also non-motor functions such as cognition and affect, only during the last 5 years it has become evident that the ...
Qianying Ma   +108 more
core   +2 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Overexpression of Mutant Ataxin-3 in Mouse Cerebellum Induces Ataxia and Cerebellar Neuropathology

open access: yes, 2013
Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is a fatal, dominant neurodegenerative disorder caused by the polyglutamine-expanded protein ataxin-3. Clinical manifestations include cerebellar ataxia and pyramidal signs
Isabel Nascimento-Ferreira   +13 more
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Altered Cerebro-Cerebellar Effective Connectivity in New-Onset Juvenile Myoclonic Epilepsy

open access: yesBrain Sciences, 2022
(1) Objective: Resting-state fMRI studies have indicated that juvenile myoclonic epilepsy (JME) could cause widespread functional connectivity disruptions between the cerebrum and cerebellum.
Laiyang Ma   +9 more
doaj   +1 more source

The role of secretin in the cerebellum

open access: yes, 2006
There is increasing interest in the role played by secretin in the central nervous system. Recent evidence suggests that this peptide is widely expressed in the brain but some areas, notably the cerebellum, show a prominent expression of the peptide and ...
Chan, Y, Yung, W, Wang, J, Chow, B
core   +1 more source

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