Results 61 to 70 of about 218,927 (266)

Histological Study of The Cerebellum In Adult Quail Coturnix coturnix (Linnaeus, 1858)

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
 A histological study was conducted to examine the structure of Cerebellum in Coturnix coturnix (Linnaeus). The results showed that the cerebellum is a portion of the Rhombencephalon and Metencephalon lying behind the cerebrum, the surface of the ...
Asmaa B.Abid , Nahla A. Al-Bakri
doaj  

Selective recruitment of the cerebellum evidenced by task-dependent gating of inputs

eLife
Functional magnetic resonance imaging (fMRI) studies have documented cerebellar activity across a wide array of tasks. However, the functional contribution of the cerebellum within these task domains remains unclear because cerebellar activity is often ...
Ladan Shahshahani, Maedbh King, Caroline Nettekoven, Richard B Ivry, Jörn Diedrichsen   +4 more
doaj   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood

Neurobiology of Disease, 2012
PDSS2 is a gene that encodes one of the two subunits of trans-prenyl diphosphate synthase that is essential for ubiquinone biosynthesis. It is known that mutations in PDSS2 can cause primary ubiquinone deficiency in humans and a similar disease in mice ...
Song Lu, Lin-Yu Lu, Meng-Fei Liu, Qiu-Ju Yuan, Mai-Har Sham, Xin-Yuan Guan, Jian-Dong Huang   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Low-Intensity Transcranial Ultrasound Stimulation Modulates the Excitability of Motor Cortical Neural Activity by Stimulating the Cerebellum

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Functional connectivity between the cerebellum and the motor cortex is critical for motor function. Low-intensity transcranial ultrasound stimulation (TUS) has been proved to directly activate cerebellar neural activity.
Huifang Yang, Zhe Zhao, Renhao Xu, Jiamin Pei, Jiaqing Yan, Xiangjian Zhang, Hanna Lu, Yi Yuan   +7 more
doaj   +1 more source

Brain functional changes in patients with botulism after illegal cosmetic injections of botulinum toxin: A resting-state fMRI study.

PLoS ONE, 2018
BackgroundBotulinum toxin type A (BoNT-A) is generally considered safe and is widely used to treat a variety of clinical conditions involving muscle hyperactivity and for cosmetic purposes.
Ge-Fei Li, Shiyu Ban, Mengxing Wang, Jilei Zhang, Haifeng Lu, Yan-Hui Shi, Xin-Wei He, Yi-Lan Wu, Peng Peng, Yi-Sheng Liu, Mei-Ting Zhuang, Rong Zhao, Xiao-Lei Shen, Qiang Li, Jian-Ren Liu, Xiaoxia Du   +15 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood

Frontiers in Physiology, 2019
Systemic hypoxia-ischemia (HI) often occurs during preterm birth in human. HI induces injuries to hinder brain cells mainly in the ipsilateral forebrain structures.
Eduardo Farias Sanches, Yohan van de Looij, Yohan van de Looij, Audrey Toulotte, Stéphane Vladimir Sizonenko, Hongxia Lei   +5 more
doaj   +1 more source