Results 71 to 80 of about 165,475 (265)
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
BMC Neurology, 2019 Background Ischemic stroke is a leading cause of mortality and morbidity worldwide. Stenosis or blockage of an artery from atherosclerosis can cause insufficient cerebral blood supply, which leads to ischemic stroke.
Yan Jiang +3 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Cerebral venous disorders: diagnosis, clinical features
Неврология, нейропсихиатрия, психосоматика, 2014 Most reports on vascular pathology of the brain have been devoted to arterial blood flow, while morphometric studies of the brain have demonstrated that approximately 85% of the vascular bed of the brain accounts for venous vessels, 10% accounts for the ...
E. I. Chukanova +2 more
doaj +1 more source
Advanced Science, EarlyView.A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li +14 more
wiley +1 more source
The Arterial Circle of the Brain in the Bawean Deer (Axis kuhlii)
AnimalsThe Bawean deer (Axis kuhlii) is a small deer species endemic to the island of Bawean in Indonesia. The species is listed as critically endangered by the IUCN Red List. The current population is assessed to be less than 500 adults living in the wild. The
Maciej Zdun +5 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng +14 more
wiley +1 more source
Erythropoietin in vasospasm. From bench to bedside?
Brazilian Neurosurgery, 2014 Aneurysmal subarachnoid haemorrhage is one of the most deleterious acute neurological diseases. The cerebral ischemia secondary to arterial vasospasm occurring after aneurysmal subarachnoid haemorrhage is still responsible for the considerable morbidity ...
Leonardo Christiaan Welling +3 more
doaj +1 more source
Advanced Science, EarlyView.Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen +6 more
wiley +1 more source