Results 121 to 130 of about 1,957,845 (343)

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang   +10 more
wiley   +1 more source

Microsurgical Treatment of Posterior Cerebral Artery Aneurysm (P2P Segment): Case Report and Review of the Literature [PDF]

, 2018
Lucas Meguins, Antônio Ronaldo Spotti, Jean Gonçalves de Oliveira, Carlos Umberto Pereira, Ronaldo Fernandes, Herbert Santos, Linoel Curado Valsechi, Thayanna Bentes Lemanski Lopes Rodrigues, Dionei de Morais   +8 more
openalex   +1 more source

Blood Flow Distribution in Cerebral Arteries

Journal of Cerebral Blood Flow and Metabolism, 2015
L. Zarrinkoob, K. Ambarki, A. Wåhlin, R. Birgander, A. Eklund, J. Malm   +5 more
semanticscholar   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2015
Zsolt Springó, Stefano Tarantini, Peter Toth, Zsuzsanna Tucsek, A. Koller, W. Sonntag, A. Csiszar, Z. Ungvari   +7 more
semanticscholar   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

A PLCγ1-Dependent, Force-Sensitive Signaling Network in the Myogenic Constriction of Cerebral Arteries

Science Signaling, 2014
Albert L. Gonzales, Ying Yang, M. Sullivan, Lindsey Sanders, Fabrice Dabertrand, David Hill-Eubanks, M. Nelson, S. Earley   +7 more
semanticscholar   +1 more source

Curvy Surface Reconstruction

Advanced Science, EarlyView.
This review introduces the concept of “general curvy surface reconstruction,” which incorporates both geometric and physical dimensions, representing an upgrade over conventional geometric reconstruction that focuses solely on spatial relationships. Particular emphasis is placed on the emerging opportunities enabled by advanced measurement techniques ...
Chen Shang, Haoyu Qi, Zhigang Wang, Keyu Meng, Zeye Liu, Zeng Meng, Yu Yang, Jianjun Wang, Shan Jiang   +8 more
wiley   +1 more source

Twiglike Middle Cerebral Arteries [PDF]

Neurosurgery, 2012
Ana, Rodríguez-Hernández, Susanna, Miric, Michael T, Lawton   +2 more
openaire   +2 more sources

Taking the pulse of aging: mapping pulse pressure and elasticity in cerebral arteries with optical methods.

Psychophysiology, 2014
M. Fabiani, Kathy A. Low, C. Tan, Benjamin J. Zimmerman, Mark A. Fletcher, N. Schneider-Garces, E. Maclin, A. Chiarelli, B. Sutton, G. Gratton   +9 more
semanticscholar   +1 more source