Results 91 to 100 of about 1,173,497 (381)

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial

Trials, 2017
Background Cerebral small vessel disease is a common cause of vascular cognitive impairment in older people, with no licensed treatment. Cerebral blood flow is reduced in small vessel disease.
Mathilde M. H. Pauls, Natasha Clarke, Sarah Trippier, Shai Betteridge, Franklyn A. Howe, Usman Khan, Christina Kruuse, Jeremy B. Madigan, Barry Moynihan, Anthony C. Pereira, Debbie Rolfe, Egill Rostrup, Caroline E. Haig, Thomas R. Barrick, Jeremy D. Isaacs, Atticus H. Hainsworth   +15 more
doaj   +1 more source

Effects of the exercise in the cerebral blood flow and metabolism. A review [PDF]

, 2015
In recent years it has been shown that cerebral blood flow is affected by intense exercise, what may even lead to a reduction in the cognitive capacity.
Llana Belloch, Salvador, Lucas-Cuevas, Ángel Gabriel, Priego Quesada, José Ignacio, Pérez-Soriano, Pedro   +3 more
core   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Experimental carotid baroreceptor stimulation reduces blood flow velocities in the anterior and middle cerebral arteries of healthy individuals

Journal of Physiological Sciences, 2023
This study investigated effects of experimental baroreceptor stimulation on bilateral blood flow velocities in the anterior and middle cerebral arteries (ACA and MCA) using functional transcranial Doppler sonography. Carotid baroreceptors were stimulated
Gustavo A. Reyes del Paso, Casandra I. Montoro, J. Richard Jennings, Stefan Duschek   +3 more
doaj   +1 more source

Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7T [PDF]

, 2014
Decreases in stimulus-dependent blood oxygenation level dependent (BOLD) signal and their underlying neurovascular origins have recently gained considerable interest.
Aneurin J. Kennerley, Bandettini, Berwick, Blockley, Bohraus, Boorman, Boulant, Buxton, Buxton, Chen, Cohalan, Dimo Ivanov, Donahue, Donahue, Duvernoy, Galassi, Goense, Goense, Goense, Gray, Harald E. Möller, Harel, Hillman, Hua, Huber, Huber, Hurley, Hutchison, Ivanov, Jiang, Jin, Jin, Jochimsen, Jozien Goense, Jöran Lepsien, Keller, Kennerley, Kennerley, Kennerley, Kim, Kim, Kim, Kim, Kim, Kim, Laurentius Huber, Lee, Liu, Logothetis, Logothetis, Lu, Lu, Lu, Mandeville, Martin, Martindale, Moradi, Mullinger, Pasley, Payne, Pfeuffer, Raz, Robert Trampel, Robert Turner, Schridde, Schäfer, Shih, Shin, Shmuel, Shmuel, Smirnakis, Smith, Stefanovic, Stefanovic, Steffen N. Krieger, Tajima, Takano, Turner, Vafaee, Wade, Weber, Wehrli, Wong, Woolsey, Worsley, Xie, Yang, Yaseen, Zappe, Zhao, Zong   +90 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Neuroprotective Effects of Kangen-karyu on Spatial Memory Impairment in an 8-Arm Radial Maze and Neuronal Death in the Hippocampal CA1 Region Induced by Repeated Cerebral Ischemia in Rats

Journal of Pharmacological Sciences, 2009
In the present study, we investigated the neuroprotective effects of Kangen-karyu (KGK) in a repeated cerebral ischemia model (2 × 10 min, 1-h interval).
Fengling Pu, Kyoko Motohashi, Tomohiro Kaneko, Yurika Tanaka, Naomi Manome, Keiichi Irie, Jirou Takata, Nobuaki Egashira, Ryozo Oishi, Takuya Okamoto, Yasuo Sei, Takako Yokozawa, Kenichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara   +14 more
doaj   +1 more source

REGULATION OF CEREBRAL BLOOD FLOW IN HUMANS: PHYSIOLOGY AND CLINICAL IMPLICATIONS OF AUTOREGULATION.

Physiological Reviews, 2021
J. Claassen, D. Thijssen, R. Panerai, F. Faraci   +3 more
semanticscholar   +1 more source

Model estimation of cerebral hemodynamics between blood flow and volume changes: a data-based modeling approach [PDF]

, 2008
It is well known that there is a dynamic relationship between cerebral blood flow (CBF) and cerebral blood volume (CBV). With increasing applications of functional MRI, where the blood oxygen-level-dependent signals are recorded, the understanding and ...
Billings, S.A., Coca, D., Li, L.M., Mayhew, J.E.W., Pan, Y., Wei, H.L., Zheng, Y.   +6 more
core   +2 more sources