Results 81 to 90 of about 9,788 (221)

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar   +10 more
wiley   +1 more source

Symptomatic capillary telangiectasia of the pons and intracerebral developmental venous anomaly – a rare association [Simptomatska kapilarna teleangiektazija ponsa i intracerebralna razvojna venska anomalija: prikaz slučaja] [PDF]

open access: yes, 2011
Various combinations of vascular malformations of the brain in one lesion have been reported, while others seem to be very rare. In this report, the authors discuss the case of a coexistence of an capillary telangiectasia of the pons and intracerebral ...
Markeljević, Jasenka   +5 more
core  

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

open access: yesInterdisciplinary Medicine, Volume 3, Issue 5, September 2025.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang   +4 more
wiley   +1 more source

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

open access: yesNature Communications, 2019
Cerebral Cavernous Malformations (CCM) are often caused by mutations in CCM1/KRIT1. Here, Chapman et al. elegantly show that the CCM complex promotes apoptosis by regulating zinc homeostasis and storage via a conserved mechanism that likely generates the
Eric M. Chapman   +14 more
doaj   +1 more source

Zebrafish models of cerebrovascular disease [PDF]

open access: yes, 2014
Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease ...
Peterson, Randall T, Walcott, Brian P
core   +1 more source

Treatment of Cerebral Cavernous Malformations Presenting With Seizures: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Neurology, 2020
Background: Cerebral cavernous malformations (CCMs) presenting with seizures can be treated with neurosurgery or radiosurgery, but the ideal treatment remains unclear.
Xiangyu Gao   +9 more
doaj   +1 more source

Epileptic seizures due to multiple cerebral cavernomatosis [PDF]

open access: yes, 2007
Background. Cavernous angiomas are angiographically occult vascular malformations that are present in 0.4−0.9 % of people, and represent around 5% of all cerebrovascular malformations. They can be single or multiple, and sporadic or familial.
Lukić Stevo, Spasić Mirjana
core   +1 more source

Metabolic Factors Related to Interpersonal Dysfunction in Acromegaly: A Nationwide Cross‐Sectional Study in China

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 9, September 2025.
Metabolic and physical factors—specifically frontal bossing, cardiovascular comorbidities, and elevated preoperative GH levels—are independent predictors of severe interpersonal dysfunction in Chinese patients with acromegaly. These findings underscore the need for integrating systematic psychosocial screening into routine neuroendocrine management to ...
Shashi Kiran Tagilapalli   +13 more
wiley   +1 more source

Pediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes. [PDF]

open access: yes, 2016
OBJECTIVE Intracranial dural arteriovenous fistulas (DAVFs) are rare in children. This study sought to better characterize DAVF presentation, angioarchitecture, and treatment outcomes.
Amans, Matthew R   +8 more
core   +1 more source

Cerebral Cavernous Malformations [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2000
I, Fleetwood, W, Hu, M, Hudon
openaire   +2 more sources

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