Results 61 to 70 of about 9,652 (216)

CCM3 and cerebral cavernous malformation disease [PDF]

Stroke and Vascular Neurology, 2019
Cerebral cavernous malformations (CCMs) are vascular lesions characterised by enlarged and irregular structure of small blood vessels in the brain, which can result in increased risk of stroke, focal neurological defects and seizures. Three different genes, CCM1/Krev/Rap1 Interacting Trapped 1, CCM2/MGC4607 and CCM3/PDCD10, are associated with the CCMs’
Kang Wang, Huanjiao Jenny Zhou, Min Wang
openaire   +2 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 972-983, May 2026.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Multiple intracranial cavernous angiomas: A rare case series

Journal of the Scientific Society, 2012
Cavernous angiomas are cerebral cavernous malformations and they are relatively rare lesions. Two forms of cavernous angiomas have been described: a sporadic form, in which patients usually have a single lesion, and a familial form, the hallmarks of ...
Pradeepgoud H Patil, A C Shetti, Ashwin S Patil, Vinaykumar C Udasi, Kiran S Desai, Tejas B Gosalia   +5 more
doaj   +1 more source

Postzygotic mosaicism in cerebral cavernous malformation [PDF]

Journal of Medical Genetics, 2019
Background Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesions in conjunction ...
Rath, M., Pagenstecher, Axel, Hoischen, A., Hoischen, A., Felbor, U.   +4 more
openaire   +3 more sources

Atlas of Nervous System Vascular Malformations: A Systematic Review

Life, 2022
Vascular malformations are frequent in the head and neck region, affecting the nervous system. The wide range of therapeutic approaches demand the correct anatomical, morphological, and functional characterization of these lesions supported by imaging ...
Carlos Castillo-Rangel, Gerardo Marín, Karla Aketzalli Hernandez-Contreras, Cristofer Zarate-Calderon, Micheel Merari Vichi-Ramirez, Wilmar Cortez-Saldias, Marco Antonio Rodriguez-Florido, Ámbar Elizabeth Riley-Moguel, Omar Pichardo, Osvaldo Torres-Pineda, Helena G. Vega-Quesada, Ramiro Lopez-Elizalde, Jaime Ordoñez-Granja, Hugo Helec Alvarado-Martinez, Luis Andrés Vega-Quesada, Gonzalo Emiliano Aranda-Abreu   +15 more
doaj   +1 more source

Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging

VIEW, Volume 7, Issue 2, April 2026.
Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao, Jingyu Deng, Qin Li, Tong Xia, Xun Yang, Simei Yang, Changzhen Sun, Xia Xiong, Li Liu   +8 more
wiley   +1 more source

Limited Impact of Serial Follow-Up Imaging in Clinically Stable Patients With Brainstem Cavernous Malformations

Frontiers in Neurology, 2020
Background: Clinical management of patients with brainstem cavernous malformations (BSCM) is often challenging due to the unpredictable clinical course and lack of high-quality evidence.
Julia Velz, Julia Velz, Flavio Vasella, Flavio Vasella, Yang Yang, Yang Yang, Marian Christoph Neidert, Marian Christoph Neidert, Luca Regli, Luca Regli, Oliver Bozinov, Oliver Bozinov   +11 more
doaj   +1 more source

PDCD10 gene mutations in multiple cerebral cavernous malformations. [PDF]

PLoS ONE, 2014
Cerebral cavernous malformations (CCMs) are vascular abnormalities that may cause seizures, intracerebral haemorrhages, and focal neurological deficits.
Maria Sole Cigoli, Francesca Avemaria, Stefano De Benedetti, Giovanni P Gesu, Lucio Giordano Accorsi, Stefano Parmigiani, Maria Franca Corona, Valeria Capra, Andrea Mosca, Simona Giovannini, Francesca Notturno, Fausta Ciccocioppo, Lilia Volpi, Margherita Estienne, Giuseppe De Michele, Antonella Antenora, Leda Bilo, Antonietta Tavoni, Nelia Zamponi, Enrico Alfei, Giovanni Baranello, Daria Riva, Silvana Penco   +22 more
doaj   +1 more source

Paradoxical Worsening of Ocular Symptoms after Spontaneous Closure of a Carotid Cavernous Fistula: Case Report [PDF]

, 2012
We report an interesting case of a spontaneous occlusion of a carotid cavernous fistula (CCF) causing a paradoxical worsening of orbital symptoms. A 59-year-old woman presented to our institution with conjunctival injection, raised intraocular pressures (
Bilyk, MD, Jurij R., Chalouhi, MD, Nohra, Dumont, MD, Aaron S., Gonzalez, MD, L. Fernando, Jabbour, MD, Pascal, Rosenwasser MD, Robert H., Tjoumakaris, MD, Stavropoula   +6 more
core   +2 more sources

Cerebral Venous Outflow Insufficiency: A Study on Symptoms and Venous Stenosis Classification

MedComm, Volume 7, Issue 3, March 2026.
Cerebral venous outflow insufficiency (CVOI) predominantly consists of 10 cerebral venous congestion symptoms. Based on the traditional classification according to imaging features, this study classified CVOI into intracranial (CV), extracranial (JV), and tandem (CJV) types, which better reflect the imaging features and pathological types of patients ...
Hui Li, Xiaojiao Guan, Lu Liu, Chunxiao Lu, Weiyue Zhang, Yifan Zhou, Huimin Jiang, Chenxia Zhou, Jian Dong, Xunming Ji, Chen Zhou   +10 more
wiley   +1 more source