Results 81 to 90 of about 634,872 (202)

Review of familial cerebral cavernous malformations and report of seven additional families

, 2016
Cerebral cavernous malformations are vascular anomalies of the central nervous system characterized by clusters of enlarged, leaky capillaries. They are caused by loss-of-function mutations in KRIT1, CCM2, or PDCD10.
van Steensel, Maurice A. M., de Vos, Ivo J. H. M., Vreeburg, Maaike, Koek, Ger H.   +3 more
core   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 9, Page 2138-2155, October 2026.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment

The Scientific World Journal, 2015
Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches.
Nikolaos Mouchtouris, Nohra Chalouhi, Ameet Chitale, Robert M. Starke, Stavropoula I. Tjoumakaris, Robert H. Rosenwasser, Pascal M. Jabbour   +6 more
doaj   +1 more source

Reducing the dose delivered to major intracranial blood vessels in brain radiotherapy using spot‐scanning proton arc therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Glioblastoma (GBM) patients have poor clinical prognoses, which may partially be explainable by correlations between radiation‐induced killing of circulating blood cells (CBCs) and worse clinical outcomes. Proton radiotherapy is currently delivered via intensity‐modulated proton therapy (IMPT), for which the target is irradiated ...
Peilin Liu, Sebastian Tattenberg, Xiaoda Cong, Peter Y. Chen, Xuanfeng Ding, Abdelkhalek Hammi   +5 more
wiley   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, Volume 13, Issue 53, 24 September 2026.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Accuracy of SWI sequences compared to T2*-weighted gradient echo sequences in the detection of cerebral cavernous malformations in the familial form

, 2016
The purpose of this study was to assess the accuracy of susceptibility-weighted imaging (SWI), compared with T2*-weighted gradient echo (GRE) imaging in assessing cerebral cavernous ...
MIDIRI, Massimo, Banco, A., Bencivinni, F., SPECIALE, Claudia, SPARACIA, Gianvincenzo   +4 more
core   +1 more source

Cerebral Cavernous Malformations [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2000
I, Fleetwood, W, Hu, M, Hudon
openaire   +2 more sources

Variable expression of cerebral cavernous malformations in carriers of a premature termination codon in exon 17 of the Krit1 gene

BMC Neurology, 2003
Background Cerebral cavernous malformations (CCM) present as either sporadic or autosomal dominant conditions with incomplete penetrance of symptoms. Differences in genetic and environmental factors might be minimized among first-degree relatives.
Gamero Miguel A, Solano Francisca, García-Moreno José M, Costa Alzenire F, Lucas Miguel, Izquierdo Guillermo   +5 more
doaj   +1 more source

De novo MGC4607 gene heterozygous missense variants in a child with multiple cerebral cavernous malformations

, 2012
Cavernous malformations are angiographically occult, low-pressure neurovascular lesions with distinct imaging and clinical characteristics; main clinical manifestations are seizure, focal neurological deficits and epileptic attacks.
CIGOLI, MARIA SOLE, M. Pavanello, F. Avemaria, S. Penco, S. Pileggi, L. Mosca, V. Capra, C. Tarlarini, P. De Marco, A. Marocchi   +9 more
core   +1 more source

Cerebral cavernous malformations: From molecular pathogenesis to genetic counselling and clinical management

, 2011
Cerebral cavernous (or capillary-venous) malformations (CCM) have a prevalence of about 0.1-0.5% in the general population. Genes mutated in CCM encode proteins that modulate junction formation between vascular endothelial cells.
Maat-Kievit, A.A. (Anneke), Duckers, H.J. (Henricus), Remco A Haasdijk, Haasdijk, R.A. (Remco), Cheng, C. (Caroline), Caroline Cheng, Anneke J Maat-Kievit, Henricus J Duckers, Maat-Kievit, JA, Duckers, Eric, Haasdijk, Remco, Cheng, Caroline   +11 more
core   +1 more source