Results 181 to 190 of about 551,373 (269)

Multi‐Omics Insights Into Circulating T‐Cell Metabolic Reprogramming and Treg Dysfunction in Moyamoya Disease

open access: yesMedComm, Volume 7, Issue 11, November 2026.
The comprehensive study design is illustrated. A multi‐omics approach was used to characterize T‐cell metabolic alterations in MMD. By integrating mass cytometry (CyTOF), single‐cell RNA sequencing (scRNA‐seq), bulk RNA‐seq, metabolomics, and flow cytometry, we aimed to elucidate metabolic reprogramming in circulating T cells and Treg dysfunction in ...
Zhiyao Zheng   +12 more
wiley   +1 more source

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

open access: yesArtificial Organs, Volume 50, Issue 11, Page 1657-1667, November 2026.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto   +11 more
wiley   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1219-1233, November 2026.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala   +13 more
wiley   +1 more source

BATMAN-Assisted Valve-in-Valve TMVR With Planned Hemodynamic Support in Severe Pulmonary Hypertension. [PDF]

open access: yesJACC Case Rep
Saeed M   +6 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6422-6443, November 2026.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn   +10 more
wiley   +1 more source

Mechanical circulatory support for haemodynamic protection in patients with heart failure during non-cardiac surgery. [PDF]

open access: yesAm Heart J Plus
Pfeffer TJ   +9 more
europepmc   +1 more source

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