Results 121 to 130 of about 1,609,795 (412)
Oxidized Carbon Nanoparticles Enhance Cellular Energetics With Application to Injured Brain
Oxidized carbon nanozymes (OCNs) that catalyze the dismutation of superoxide radical and oxidation of reduced nicotinamide adenine dinucleotide (NADH) to NAD+ promote glycolytic and mitochondrial energy metabolism under impaired conditions observed in traumatic brain injury with hemorrhage.
Karthik Mouli+11 more
wiley +1 more source
Critical appraisal on mitochondrial dysfunction in Alzheimer’s disease
Amyloid plaques deposit on neurons in case of Alzheimer's Disease. Mitochondria play a vital role in pathogenesis of Alzheimer's Disease. Mitochondrial dysfunction can lead to formation of mPTP, alteration of complexes 1,3 and 4, deficits in bioenergetics with impaired mitochondrial biogenesis. Abstract It is widely recognized that Alzheimer's disease (
Faizan Ahmad, Punya Sachdeva
wiley +1 more source
Nicotiflorin is a flavonoid extracted from Carthamus tinctorius. Previous studies have shown its cerebral protective effect, but the mechanism is undefined.
Guang-qiang Hu+5 more
doaj +1 more source
Revealing Cortical Layers In Histological Brain Images With Self-Supervised Graph Convolutional Networks Applied To Cell-Graphs [PDF]
Identifying cerebral cortex layers is crucial for comparative studies of the cytoarchitecture aiming at providing insights into the relations between brain structure and function across species. The absence of extensive annotated datasets typically limits the adoption of machine learning approaches, leading to the manual delineation of cortical layers ...
arxiv
Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]
Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali+23 more
core +3 more sources
Development and Evolution of Cerebral and Cerebellar Cortex
Cerebral cortex and cerebellar cortex both vary enormously across species in their size and complexity of convolutions. We discuss the development and evolution of cortical structures in terms of anatomy and functional organization.
D. V. Van Essen+2 more
semanticscholar +1 more source
Researchers demonstrate a diamond‐based, wireless biointerface capable of generating safe capacitive current under pulsed light illumination in the visible and near‐infrared light region. This biointerface is long‐lasting and the first among diamond‐based electrodes capable of optically‐controlled, non‐genetic modulation of intracellular calcium ...
Yue Yao+4 more
wiley +1 more source
How the brain represents the reward value of fat in the mouth. [PDF]
The palatability and pleasantness of the sensory properties of foods drive food selection and intake and may contribute to overeating and obesity. Oral fat texture can make food palatable and pleasant.
De Souza, Arun+3 more
core +2 more sources
Network structure of cerebral cortex shapes functional connectivity on multiple time scales
Neuronal dynamics unfolding within the cerebral cortex exhibit complex spatial and temporal patterns even in the absence of external input. Here we use a computational approach in an attempt to relate these features of spontaneous cortical dynamics to ...
C. Honey+3 more
semanticscholar +1 more source
Actuated Hydrogel Platforms To Study Brain Cell Behavior
The complex and dynamic viscoelastic properties of the brain underpin neural plasticity and overall function. Actuating hydrogel platforms support mechanistic research to elucidate how brain cells respond to dynamic microenvironments. This study reviews the mechanobiology of the brain and its impact on brain function in health and disease and describes
Kirill E. Zhurenkov+3 more
wiley +1 more source