Results 161 to 170 of about 1,638,797 (414)
Advanced Science, EarlyView.PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou +7 more
wiley +1 more source
Croonian Lectures on the Significance of the Cerebral Cortex: Delivered before the Royal College of Physicians of London, June, 1919 [PDF]
, 1919 G. E. Smith
openalex +1 more source
Brain : a journal of neurology, 2015 Perfusion is reduced in the cerebral neocortex in Alzheimer's disease. We have explored some of the mechanisms, by measurement of perfusion-sensitive and disease-related proteins in post-mortem tissue from Alzheimer's disease, vascular dementia and age ...
T. Thomas, S. Miners, S. Love
semanticscholar +1 more source
Advanced Science, EarlyView.A region‐wise functional connectivity dynamics (FCD) switching index (RFSI) identifies abnormal drivers in ASD across development, linked to salience/ventral attention, default mode, and frontoparietal networks. RFSI changes correlate with transcriptomic and neurotransmitter profiles, and supported by gene‐edited ASD monkeys.
Wei Li +11 more
wiley +1 more source
Coordinated scaling of cortical and cerebellar numbers of neurons
Frontiers in Neuroanatomy, 2010 While larger brains possess concertedly larger cerebral cortices and cerebella, the relative size of the cerebral cortex increases with brain size, but relative cerebellar size does not.
Suzana Herculano-Houzel
doaj +1 more source
Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex
Journal of Neuroscience, 2013 Neurogenesis must be properly regulated to ensure that cell production does not exceed the requirements of the growing cerebral cortex, yet our understanding of mechanisms that restrain neuron production remains incomplete.
Christopher L Cunningham +2 more
semanticscholar +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
Advanced Science, EarlyView.This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang +16 more
wiley +1 more source
Effect of soy milk on thickness of cerebral cortex and hippocampus in newborn ovariectomized rats
Armaghane Danesh Bimonthly Journal, 2014 Background & aim: Soy contains the largest concentration of isoflavones, they are structurally similar to estradiol and mimic its effects. The purpose of this study was to evaluate the effect of soy milk on thickness of cerebral cortex and hippocampus in
B Marzban Abbas Abadi +2 more
doaj
Advanced Science, EarlyView.Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang +11 more
wiley +1 more source